| 產(chǎn)品編號 | bs-2454R |
| 英文名稱 | CCL19 Rabbit pAb |
| 中文名稱 | 巨噬細(xì)胞炎性蛋白19抗體 |
| 別 名 | Macrophage Inflammatory Protein 3β; ; Macrophage Inflammatory Protein 3 beta; beta chemokine exodus 3; C C chemokine ligand 19; CC chemokine ligand 19; CCL19; Chemokine(C C motif) ligand 19; Chemokine(CC motif) ligand 19; Chemokine CC Motif Ligand 19; CK |
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Specific References (3) | bs-2454R has been referenced in 3 publications.
[IF=4.873] Xinli Niu. et al. Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration. J Nutr Biochem. 2021 Mar;89:108560 IF ; Mouse.
[IF=2.23] Borrelli, G. M., et al. "Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes." Reproductive Sciences (2015): 1933719115592711. IHC-P ; Human.
[IF=0] Borrelli, Giuliano. Investigation of invasion factors in deep-infiltrating endometriosis. Diss. Freie Universit?t Berlin, 2015. IHC-P ; Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 自然殺傷細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 9.2 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCL19: 26-108/108 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008] Function: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Specifically binds to chemokine receptor CCR7. Subcellular Location: Secreted. Tissue Specificity: Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus. Similarity: Belongs to the intercrine beta (chemokine CC) family. SWISS: O70460 Gene ID: 24047 Database links: Entrez Gene: 6363 Human Entrez Gene: 24047 Mouse Omim: 602227 Human SwissProt: Q99731 Human SwissProt: O70460 Mouse Unigene: 50002 Human Unigene: 426373 Mouse Unigene: 441169 Mouse Unigene: 459263 Mouse Unigene: 6660 Mouse
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