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CD39L4 Rabbit pAb (bs-6526R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-6526R
英文名稱 CD39L4 Rabbit pAb
中文名稱 原癌基因CD39樣蛋白4/ENTPD5抗體
別    名 CD39 like 4; AI196558; AI987697; CD39 antigen like 4; CD39 antigen-like 4; CD39 like 4; CD39L4; Ectonucleoside triphosphate diphosphohydrolase 5; ENTP5_HUMAN; Entpd5; ER UDPase; ER-UDPase; GDPase ENTPD5; Guanosine-diphosphatase ENTPD5; MGC163357; MGC163359; mNTPase; NTPDase 5; Nucleoside diphosphatase; PCPH; Pcph proto oncogene protein; Proto oncogene CPH; UDPase ENTPD5; Uridine-diphosphatase ENTPD5  
Specific References  (1)     |     bs-6526R has been referenced in 1 publications.
[IF=3.725] Moyuru Hayashi. et al. Water intake accelerates ATP release from myofibroblast cells in rats: ATP-mediated podoplanin-dependent control for physiological function and immunity. Am J Physiol-Gastr L. 2021 Jan;320(1):G54-G65  
研究領(lǐng)域 腫瘤  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  腫瘤細胞生物標(biāo)志物  新陳代謝  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENTPD5/CD39L4: 331-380/428 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.

Function:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling

Subcellular Location:
Endoplasmic reticulum membrane, Single-pass type II membrane protein

Tissue Specificity:
Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.

Post-translational modifications:
N-glycosylated; high-mannose type

Similarity:
Belongs to the GDA1/CD39 NTPase family.

SWISS:
O75356

Gene ID:
957

Database links:

Entrez Gene: 957 Human

Entrez Gene: 12499 Mouse

Entrez Gene: 314312 Rat

Omim: 603162 Human

SwissProt: O75356 Human

SwissProt: Q9WUZ9 Mouse

SwissProt: Q6P6S9 Rat

Unigene: 720540 Human

Unigene: 10211 Mouse

Unigene: 63533 Rat



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