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HOXB8 Rabbit pAb (bs-6539R)  
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產品編號 bs-6539R
英文名稱 HOXB8 Rabbit pAb
中文名稱 同源盒蛋白B8抗體
別    名 Homeobox B8; Homeobox protein Hox B8; Homeobox protein HoxB8; HOX 2; Hox 2.4; HOX 2D; HOX B8; HOX2; Hox2.4; HOX2D; HOXB8; HXB8_HUMAN.  
Specific References  (1)     |     bs-6539R has been referenced in 1 publications.
[IF=2.058] Liu, Lidan. et al. The roles of HOXB8 through activating Wnt/β-catenin and STAT3 signaling pathways in the growth, migration and invasion of ovarian cancer cells. Cytotechnology. 2022 Jan;:1-11  WB,IHC ;  Human.  
研究領域 腫瘤  染色質和核信號  信號轉導  干細胞  轉錄調節(jié)因子  細胞表面分子  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Cow,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOXB8: 11-110/243 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
P17481

Gene ID:
3218

Database links:

Entrez Gene: 3218 Human

Entrez Gene: 15416 Mouse

Entrez Gene: 24457 Rat

Omim: 142963 Human

SwissProt: P17481 Human

SwissProt: P09632 Mouse

SwissProt: P18863 Rat

Unigene: 514292 Human

Unigene: 4822 Mouse

Unigene: 223006 Rat



產品圖片
Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Mouse Large intestine tissue lysates Primary: Anti-HOXB8 (bs-6539R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kDa Observed band size: 30 kDa
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