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LDOC1 Rabbit pAb (bs-6543R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-6543R
英文名稱 LDOC1 Rabbit pAb
中文名稱 癌癥亮氨酸拉鏈下調因子1抗體
別    名 BCUR1; Breast cancer up regulated 1; Breast cancer upregulated 1; Gm366; Leucine zipper down regulated in cancer 1; Leucine zipper protein down regulated in cancer cells; Leucine zipper protein down regulated in cancer cells; Mar7; Mart7; Protein LDOC1; RGD1565644; LDOC1_HUMAN .  
研究領域 腫瘤  染色質和核信號  信號轉導  轉錄調節(jié)因子  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Rabbit,Pig,Dog,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LDOC1: 65-146/146 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008].

Function:
May have an important role in the development and/or progression of some cancers.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed with high levels in brain and thyroid and low expression in placenta, liver and leukocytes. Expressed as well in six of the seven human breast cancer cell lines examined.

Similarity:
Belongs to the LDOC1 family.

SWISS:
O95751

Gene ID:
23641

Database links:

Entrez Gene: 23641 Human

Omim: 300402 Human

SwissProt: O95751 Human

Unigene: 45231 Human



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