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Upstream Binding Protein 1 Rabbit pAb (bs-6730R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-6730R
英文名稱 Upstream Binding Protein 1 Rabbit pAb
中文名稱 上游結(jié)合蛋白1抗體
別    名 LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1: 351-450/540 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Function:
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

Subunit:
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

Similarity:
Belongs to the grh/CP2 family. CP2 subfamily.

SWISS:
Q9NZI7

Gene ID:
7342

Database links:

Entrez Gene: 7342 Human

Entrez Gene: 22221 Mouse

Entrez Gene: 301038 Rat

Omim: 609784 Human

SwissProt: Q86Y57 Human

SwissProt: Q9NZI7 Human

SwissProt: Q60786 Mouse

SwissProt: Q811S7 Mouse

SwissProt: Q8BH21 Mouse

Unigene: 118041 Human

Unigene: 729120 Human

Unigene: 28052 Mouse

Unigene: 386808 Mouse

Unigene: 15705 Rat



產(chǎn)品圖片
Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti- Upstream Binding Protein 1 (bs-6730R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 56 kD
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