亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久中文骚妇内射,国产精品视频第一区二区三区
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
GPR40 Rabbit pAb (bs-13535R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-13535R
英文名稱 GPR40 Rabbit pAb
中文名稱 G蛋白偶聯(lián)受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  糖尿病  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human (predicted: Mouse,Rat,Pig,Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40: 121-220/300 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
O14842

Gene ID:
2864

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



產(chǎn)品圖片
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR40 Polyclonal Antibody, Unconjugated(bs-13535R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
免费一级肉体全黄毛片365看片 | 成人影片麻豆国产影片免费观看 | 成 人 黄 色 免费 网站无毒 | 日韩欧无码一区二区三区免费不卡 | 综合人妻久久一区二区精品 | 国产99在线a视频 | 人人妻人人添人人爽欧美一区91 | 高潮无码精品色欲av午夜福利 | 熟女作爱一区二区视频 | 新普新京亚洲欧美日韩国产 | 国产精品久久久精品无码 | 亚洲国产高清国产拍精品 | 日韩欧美国产中文字幕 | 二级毛片在线观看 | 国产精品免费露脸视频 | 亚洲欧美日韩在线观看 | 国产午夜三级一区二区三 | 国产精品99精品无码视亚 | 精品国产90后在线观看 | 国产AV无码专区毛片 | 18禁强伦姧人妻又大又久久 | 激情男女高潮射精AV免费 | 一本色道久久88综合日韩精品 | 免费无码又爽又刺激高潮久久 | 456性欧美在线视频 玩弄放荡人妻一区二区三区 | 91热久久免费频精品黑人99 | 国产特级淫片免费看欧美日韩中文 | 不卡在线播放一区二区三区 | 黄色网站免费在线观看 | 狠狠人妻久久久久久综合 | 无码人妻精品一区二区蜜桃色 | 国产精品v欧美精品v日韩精品 | 把手戳进美女尿口里动态图 | 国产特级毛片AAAAAAA高清 | 亚洲AV无码久久久久久精品酒店 | 国产精品久久久久无码AV | 久久久久精品国产AV无码 | 久久99免费视频 | 亚洲人成www在线播放 | 久久精品无码鲁网中文电影 | 精品久久久久久亚洲精品 |