亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
一级毛片AAAAAA免费看99,忘忧草日本在线播放WWW
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
HBP1 Rabbit pAb (bs-15418R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-15418R
英文名稱 HBP1 Rabbit pAb
中文名稱 HMG盒區(qū)內(nèi)含蛋白1抗體
別    名 FLJ16340; HBP 1; HBP1_HUMAN; High mobility group box transcription factor 1; HMG box containing protein 1; HMG box transcription factor 1; HMG box-containing protein 1.  
研究領(lǐng)域 心血管  染色質(zhì)和核信號(hào)  干細(xì)胞  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HBP1: 421-514/514 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 HBP1 is a member of the HMG family of transcription factors, which are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, that mediates DNA binding. HBP-1 binds to the tumor suppressor proteins Rb and p130 and initiates cell cycle arrest.Terminal cell differentiation requires this initial cell cycle arrest followed by the coordinated expression of genes defined as tissue-specifc markers. Along with initiating the commitment to cell differentiation, the continued activity of HBP1 abrogates the expression of tissue-specific genes by associating with the MyoD proteins. In muscle cell differentiation, the MyoD family of transcription factors, which include Myf5, MyoD and myogenein, induce the expression of these cell-type specific proteins and contribute to the development of cell phenotypes. The progression of terminal differentiation is, therefore, dependent on both a decrease in HBP1 activity and the corresponding activation of MyoD-induced gene transcription.

Function:
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

Subunit:
Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 AXH domain.
Contains 1 HMG box DNA-binding domain.

SWISS:
O60381

Gene ID:
26959

Database links:

Entrez Gene: 26959 Human

Entrez Gene: 73389 Mouse

Entrez Gene: 27080 Rat

SwissProt: O60381 Human

SwissProt: Q8R316 Mouse

SwissProt: Q62661 Rat

Unigene: 162032 Human

Unigene: 390461 Mouse

Unigene: 458534 Mouse

Unigene: 89226 Rat



產(chǎn)品圖片
Sample: placenta (mouse) Lysate at 40 ug Uterus (Mouse) Lysate at 40 ug bone (Mouse) Lysate at 40 ug Primary: Anti-HBP1(bs-15418R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 63 kD
Protein: intestine(mouse) lysates at 40ug; Primary: Anti-HBP1 (bs-15418R) at 1:200; Secondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 3000; ECL excitated the fluorescence; Predicted band size : 58kD Observed band size : 58kD
Sample: Lane 1: Human Hela cell lysates Lane 2: Human MCF-7 cell lysates Lane 3: Human THP-1 cell lysates Primary: Anti- HBP1 (bs-15418R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 60 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HBP1) Polyclonal Antibody, Unconjugated (bs-15418R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
成人片免费观看WWW 久久特级av一级毛片 | 日韩AV无码一区二区三区不卡毛片 | 亚洲精品白浆高清久久久久久 | 精品极品三大极久久久久 | 最近的中文字幕在线MV视频 | 18以下不能看的美女视频 | 欧美一级二级三级 | 性色AV一区二区三区咪爱四虎 | 亚洲一区爱区精品无码 | 快穿之浪荡H啪肉NP文肉BL | 亚洲无码一区二区三区 | 午夜欧美日韩国产福利91不卡一区二区三区 | 免费视频片在线观看大片 | 欧美日本韩国一二区视频 | 亚洲中文字幕无码中文字无摸 | 中韩高清无专码区2021曰 | 2019年国产高清情侣视频 | 懂色av无码aV天天aV天天爽 | 野花香日本大全免费观看 | 在线观看免费人成视频色 | 免费一级欧美片在线观 | 精品人妻少妇久久久AV | 国产制服91一区二区三区制服 | 欧洲精欧洲精品高清一区 | 性欧美video另类hd尤物 | 校园久久综合激情四射伊人丁香 | 色噜噜人妻丝袜aV先锋影音先 | aaaaaa级特色特黄的毛片 | 精品国产乱码久久久久久浪潮小说 | 鲁一鲁AV2019在线 | 日本免费一级婬片A级中文字幕 | 亚洲精品免费网站 | 国产女高清在线看免费观看 | 91精品国产成人网在线观看 | 又湿又紧又大又爽又A视频 一二三四社区在线中文视频 | 青青手机国产在线视频 | 国产精品一区二区三区四区五区 | 亚洲国产精品高清免费在线观看 | 又黄又猛又爽大片免费 | 天天做天天爱天天爽综合网 | 国产亚洲精品AAAA片小说 |