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C19orf57 Rabbit pAb (bs-13791R)  
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產品編號 bs-13791R
英文名稱 C19orf57 Rabbit pAb
中文名稱 19號染色體開放閱讀框57抗體
別    名 C19orf57; CS057_HUMAN; Pre-T/NK cell-associated protein 3B3; Uncharacterized protein C19orf57.  
研究領域 腫瘤  細胞生物  免疫學  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 70 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C19orf57: 1-100/668 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 C19orf57 is a 668 amino acid protein that exists as two alternatively spliced isoforms and are encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

SWISS:
Q0VDD7

Gene ID:
79173

Database links:

Entrez Gene: 79173 Human

SwissProt: Q0VDD7 Human

Unigene: 143288 Human



產品圖片
Sample: Siha(human) Cell Lysate at 40 ug Primary: Anti- C19orf57 (bs-13791R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 70kD Observed band size: 63kD
Paraformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (C19orf57) Polyclonal Antibody, Unconjugated (bs-13791R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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