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KCTD3 Rabbit pAb (bs-16934R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-16934R
英文名稱 KCTD3 Rabbit pAb
中文名稱 腎細胞癌抗原NYREN 45抗體
別    名 BTB/POZ domain-containing protein KCTD3; Kctd3; KCTD3_HUMAN; MGC43935; NY REN 45; NY REN 45 antigen; NY REN45; NYREN 45; OTTHUMP00000035070; Potassium channel tetramerisation domain containing 3; Renal carcinoma antigen NY REN 45; Renal carcinoma antigen   
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 89 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCTD3: 731-815/815 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Tissue Specificity:
Broadly expressed in normal tissues.

Similarity:
Belongs to the KCTD3 family.
Contains 1 BTB (POZ) domain.
Contains 5 WD repeats.

SWISS:
Q9Y597

Gene ID:
51133

Database links:

Entrez Gene: 51133 Human

Entrez Gene: 226823 Mouse

Entrez Gene: 305055 Rat

Omim: 613272 Human

SwissProt: Q9Y597 Human

SwissProt: Q8BFX3 Mouse

Unigene: 335139 Human

Unigene: 209880 Mouse




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