| 產(chǎn)品編號(hào) | bs-17206R |
| 英文名稱 | Josephin-1 Rabbit pAb |
| 中文名稱 | JOSD1蛋白抗體 |
| 別 名 | dJ508I15.2; JOS1_HUMAN; Josd1; Josephin 1; Josephin domain containing 1; Josephin domain-containing 1; Josephin-1; KIAA0063; OTTHUMP00000198984; OTTHUMP00000239365. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Chicken,Dog,Cat,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human JOSD1: 1-100/202 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Josephin-1 is a 202 amino acid protein that contains one josephin domain and is encoded by a gene that maps to human chromosome 22. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Function: Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. Subunit: Interacts with beta-actin/ACTB. Similarity: Contains 1 Josephin domain. SWISS: Q15040 Gene ID: 9929 Database links: Entrez Gene: 9929 Human Entrez Gene: 74158 Mouse SwissProt: Q15040 Human SwissProt: Q9DBJ6 Mouse Unigene: 3094 Human Unigene: 2495 Rat |
| 產(chǎn)品圖片 |
Sample:
U937(Human) Cell Lysate at 40 ug
Primary: Anti-Josephin-1 (bs-17206R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kD
Observed band size: 27 kD
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