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Visfatin Rabbit pAb (bs-10245R)  
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產(chǎn)品編號 bs-10245R
英文名稱 Visfatin Rabbit pAb
中文名稱 內(nèi)脂素/內(nèi)臟脂肪素/前B細(xì)胞克隆增強(qiáng)因子1抗體
別    名 pre-B-cell colony-enhancing factor 1; PBEF1 protein; AI480535; 1110035O14Rik; AI314458; DKFZP666B131; EC 2.4.2.12; MGC117256; NAmPRTase; NAMPT; Nicotinamide phosphoribosyltransferase; PBEF; PBEF1; Pre B cell colony enhancing factor 1; Pre B cell colony en  
研究領(lǐng)域 心血管  免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  糖尿病  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PBEF: 401-491/491 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011].

Function:
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.

Similarity:
Belongs to the NAPRTase family.

SWISS:
P43490

Gene ID:
10135

Database links:

Entrez Gene: 10135 Human

Entrez Gene: 59027 Mouse

Entrez Gene: 297508 Rat

Omim: 608764 Human

SwissProt: P43490 Human

SwissProt: Q99KQ4 Mouse

SwissProt: Q80Z29 Rat

Unigene: 489615 Human

Unigene: 202727 Mouse

Unigene: 203508 Rat



產(chǎn)品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-Visfatin (bs-10245R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kD Observed band size: 55 kD
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