| 產(chǎn)品編號(hào) |
bs-18029R |
| 英文名稱 |
Orexin Receptor 1 Rabbit pAb
|
| 中文名稱 |
丘腦分泌素受體1抗體 |
| 別 名 |
HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1r; OX1R_HUMAN. |
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Specific References (3) | bs-18029R has been referenced in 3 publications.
[IF=5.81] Shengyan Xi. et al. The Ciji-Hua’ai-Baosheng II Formula Attenuates Chemotherapy-Induced Anorexia in Mice With H22 Hepatocellular Carcinoma. Front Pharmacol. 2021; 12: 715824 IHC ; Mouse.
[IF=3.333] Hye Ji J. Kim. et al. Dual Cannabinoid and Orexin Regulation of Anhedonic Behaviour Caused by Prolonged Restraint Stress. BRAIN SCI. 2023 Feb;13(2):314 IHC ; Mouse.
[IF=2.751] De-Qi Yan. et al. Establishment of a chronic insomnia rat model of sleep fragmentation using unstable platforms surrounded by water. EXP THER MED. 2023 May;25(5):1-12 IF ; Rat.
|
| 研究領(lǐng)域 |
腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal
|
| 交叉反應(yīng) |
Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Horse)
|
| 產(chǎn)品應(yīng)用 |
WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 |
48 kDa |
| 檢測(cè)分子量 |
|
| 細(xì)胞定位 |
細(xì)胞膜
|
| 性 狀 |
Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human Orexin Receptor 1: 101-200/425 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 緩 沖 液 |
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed |
PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]
Function:
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
O43614
Gene ID:
3062
Database links:
Entrez Gene: 3061 Human
Entrez Gene: 230777 Mouse
Entrez Gene: 25593 Rat
Omim: 602392 Human
SwissProt: O43613 Human
SwissProt: P58307 Mouse
SwissProt: P56718 Rat
Unigene: 388226 Human
Unigene: 246595 Mouse
Unigene: 88262 Rat
|
| 產(chǎn)品圖片 |
Sample: A549 Cell (Human) Lysate at 30 ug
Primary: Anti-Orexin Receptor 1 (bs-18029R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 48kD
Sample:
Lane 1: Mouse Cerebellum tissue lysates
Lane 2: Mouse Pancreas tissue lysates
Lane 3: Rat Cerebellum tissue lysates
Lane 4: Rat Pancreas tissue lysates
Primary: Anti-Orexin Receptor 1 (bs-18029R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kD
Observed band size: 48 kD
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