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NUPL1 Rabbit pAb (bs-19569R)  
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產(chǎn)品編號 bs-19569R
英文名稱 NUPL1 Rabbit pAb
中文名稱 核孔蛋白樣蛋白1抗體
別    名 KIAA0410; Nucleoporin like 1; Nucleoporin p58/p45; NUPL 1; OTTHUMP00000018146; OTTHUMP00000042323; PRO2463.  
研究領(lǐng)域 染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 61 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUPL1: 201-300/599 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Function:
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.

Subunit:
Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1. Interacts with NUTF2. Interacts with SRP1-alpha and Importin p97 proteins when they are together, but not with SRP1-alpha protein alone (By similarity).

Subcellular Location:
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note: Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter.

SWISS:
Q9BVL2

Gene ID:
9818

Database links:

Entrez Gene: 9818 Human

Entrez Gene: 71844 Mouse

Entrez Gene: 245922 Rat

Omim: 607615 Human

SwissProt: Q9BVL2 Human

SwissProt: Q8R332 Mouse

SwissProt: P70581 Rat

Unigene: 507537 Human

Unigene: 258051 Mouse

Unigene: 11099 Rat



產(chǎn)品圖片
Sample: Thymus (Rat) Lysate at 40 ug Primary: Anti-NUPL1 (bs-19569R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 63 kD
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