亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
内射精品无码中文字幕,久久91综合国产91久久精品,美女国产毛片A区内射
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
PACE4 Rabbit pAb (bs-19997R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-19997R
英文名稱 PACE4 Rabbit pAb
中文名稱 PACE4蛋白抗體
別    名 Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; PCSK6; PCSK6_HUMAN; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin like protease; Subtilisin-like proprotein convertase 4; subtilisin/kexin like protease PACE4; Subtilisin/kexin-like protease PACE4.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Rat (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 91 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACE4: 711-810/969 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014]

Function:
Likely to represent an endoprotease activity within the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues and capable of cleavage at the RX(K/R)R consensus motif.

Subcellular Location:
Secreted; Endomembrane system. Retained intracellularly probably through a hydrophobic cluster in their C-terminus and Endoplasmic reticulum. Not secreted, remains probably in zymogen form in endoplasmic reticulum.

Tissue Specificity:
Each PACE4 isoform exhibits a unique restricted distribution. Isoform PACE4A-I is expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, but at comparatively higher levels in the liver. Isoform PACE4A-II is at least expressed in placenta. Isoform PACE4B was only found in the embryonic kidney cell line from which it was isolated. Isoform PACE4C and isoform PACE4D are expressed in placenta. Isoform PACE4E-I is expressed in cerebellum, placenta and pituitary. Isoform PACE4E-II is at least present in cerebellum.

Post-translational modifications:
The PACE4A-I precursor protein seems to exist in the reticulum endoplasmic as both a monomer and a dimer-sized complex whereas mature PACE4A-I exists only as a monomer, suggesting that propeptide cleavage affects its tertiary or quaternary structure.

Similarity:
Belongs to the peptidase S8 family.
Contains 1 homo B/P domain.
Contains 1 PLAC domain.

SWISS:
P29122

Gene ID:
5046

Database links:

Entrez Gene: 524684 Cow

Entrez Gene: 488703 Dog

Entrez Gene: 100673009 Elephant

Entrez Gene: 100057677 Horse

Entrez Gene: 5046 Human

Entrez Gene: 100405129 Marmoset (common)

Entrez Gene: 18553 Mouse

Entrez Gene: 100020955 Opossum

Entrez Gene: 100152144 Pig

Entrez Gene: 25507 Rat

Omim: 167405 Human

SwissProt: P29122 Human

SwissProt: Q63415 Rat

Unigene: 498494 Human

Unigene: 665989 Human

Unigene: 950 Rat



產(chǎn)品圖片
Sample: Lane 1: Rat Testis tissue lysates Lane 2: Human 293T cell lysates Lane 3: Human HepG2 cell lysates Lane 4: Human A549 cell lysates Lane 5: Human SH-SY5Y cell lysates Primary: Anti-PACE4 (bs-19997R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 91 kDa Observed band size: 135 kDa
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
在线视频这里只有精品 | 亚洲一级毛片免费观看 | 国产精一品亚洲二区在线播放 | 亚洲AV无码一二区三区在线播放 | 伊人久久大香线蕉综合色狠狠 | 91精品国产色综合久久不卡美美 | 99久久国产精品亚洲综合看片 | a毛片免费全部播放无风险 www.一级毛片 | 亚洲成年人免费网站 | 国产欧美日韩精品一区二区三区蜜桃不卡 | 国内精品一区二区综合欧美 | 国产精品你当然比游戏重要 | 91影视永久福利免费观看 | 欧美精品人人做天天操夜夜操 | 中文字幕一级毛片无码视频 | 无码人妻AⅤ一区二区三区夏目 | 国产真实女人一级毛片 | 又粗又大又黄的少妇毛片 | 亚洲人AV永久一区二区三区久久 | a无码亚洲男人的天堂 | 少妇精品无码一区二区三区 | 成人日韩熟女高清视频一区 | 人善交video欧美 | 日韩一级精品久久久久 | 久久精品这里热有精品6 | 91无码人妻精品一区 | 6080YYY午夜理论AA片 | 国语国产呻吟刺激对白在线 | 中文字幕乱偷无码AV蜜桃 | 国产又大又粗又长硬又紧又爽 | 福利一区二区视频 | 男人的好看视频1在线观看 久久国产免费一区二区三区 | 亚洲午夜福利在线视频 | 性一交一乱一色一免费无遮挡 | 日韩一级视频在线观看播放 | 久久夜色精品国产噜噜亚洲av | 国内精品久久久久久久试看 | 国产女人18毛片水真多 | 日本黄页免费视频播放网站 | 国产精品国产三级国AV | 久久国产精品高潮一级毛片 |