亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
内射精品无码中文字幕,久久91综合国产91久久精品,美女国产毛片A区内射
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
PACE4 Rabbit pAb (bs-19997R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-19997R
英文名稱 PACE4 Rabbit pAb
中文名稱 PACE4蛋白抗體
別    名 Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; PCSK6; PCSK6_HUMAN; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin like protease; Subtilisin-like proprotein convertase 4; subtilisin/kexin like protease PACE4; Subtilisin/kexin-like protease PACE4.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Rat (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 91 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACE4: 711-810/969 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014]

Function:
Likely to represent an endoprotease activity within the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues and capable of cleavage at the RX(K/R)R consensus motif.

Subcellular Location:
Secreted; Endomembrane system. Retained intracellularly probably through a hydrophobic cluster in their C-terminus and Endoplasmic reticulum. Not secreted, remains probably in zymogen form in endoplasmic reticulum.

Tissue Specificity:
Each PACE4 isoform exhibits a unique restricted distribution. Isoform PACE4A-I is expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, but at comparatively higher levels in the liver. Isoform PACE4A-II is at least expressed in placenta. Isoform PACE4B was only found in the embryonic kidney cell line from which it was isolated. Isoform PACE4C and isoform PACE4D are expressed in placenta. Isoform PACE4E-I is expressed in cerebellum, placenta and pituitary. Isoform PACE4E-II is at least present in cerebellum.

Post-translational modifications:
The PACE4A-I precursor protein seems to exist in the reticulum endoplasmic as both a monomer and a dimer-sized complex whereas mature PACE4A-I exists only as a monomer, suggesting that propeptide cleavage affects its tertiary or quaternary structure.

Similarity:
Belongs to the peptidase S8 family.
Contains 1 homo B/P domain.
Contains 1 PLAC domain.

SWISS:
P29122

Gene ID:
5046

Database links:

Entrez Gene: 524684 Cow

Entrez Gene: 488703 Dog

Entrez Gene: 100673009 Elephant

Entrez Gene: 100057677 Horse

Entrez Gene: 5046 Human

Entrez Gene: 100405129 Marmoset (common)

Entrez Gene: 18553 Mouse

Entrez Gene: 100020955 Opossum

Entrez Gene: 100152144 Pig

Entrez Gene: 25507 Rat

Omim: 167405 Human

SwissProt: P29122 Human

SwissProt: Q63415 Rat

Unigene: 498494 Human

Unigene: 665989 Human

Unigene: 950 Rat



產(chǎn)品圖片
Sample: Lane 1: Rat Testis tissue lysates Lane 2: Human 293T cell lysates Lane 3: Human HepG2 cell lysates Lane 4: Human A549 cell lysates Lane 5: Human SH-SY5Y cell lysates Primary: Anti-PACE4 (bs-19997R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 91 kDa Observed band size: 135 kDa
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
乱码一二三乱码又大又粗 | 久久婷婷国产剧情内射白浆 | 欧美亚洲国产精品久久高清 | 欧美35页视频在线观看 | 国产秦先生大战白丝97在线 | a级毛片无码免费真人久久 国产精品视频一区二区三区不卡 | 久久久久成亚洲国产av综合精品 | 国产日产欧产精品精品浪潮 | 亚洲AV无码片一区二区三区 | 国产精品久久久久久久久免费蜜桃 | a毛片免费全部播放无风险 www.一级毛片 | 欧美人与拘牲交大全O人禾 天天躁日日躁狠狠躁日日躁黑人 | 和上司交换娇妻在线播放 | 国产乱码精品一区二区三区四川 | 亚欧洲乱码视频一二三区 | 特级做a爰片毛片免费69 | 亚洲色偷偷综合亚洲AV伊人蜜桃 | 又污又黄又无遮挡网站 | 四虎影视永久免费观看 | 国产精品福利午夜在线观看 | 特级毛片全部免费播放免下载 | 久久久久久亚洲综合网站 | 热re99久久精品国99热 | 欧美日韩精品视频二区 | 国产成人无码区免费内射一片色欲 | 久久精品国产亚洲AV无码蜜臀 | 国产伦精品一区二区三区免.费 | 国产精品视频免费观看 | 校园久久综合激情四射伊人丁香 | 精品一区二区三区无码av孕妇 | 亚洲精品乱码久久久久66国产成 | 校花系列辣h文黑人宫交 | 日韩美女做暖暖免费视频 | 一级特黄性色生活片一区二区 | 激情内射亚洲一区二区三区爱妻 | 国内精品51视频在线观看 | 最近中文字幕在线中文视频 | 中文天堂网在线最新版 | 美女黄频视频大全免费的 | 久久夜色精品国产噜噜亚洲av | 日本工口里番H彩色无遮挡全彩 |