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TSPAN6 Rabbit pAb (bs-20292R)  
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產品編號 bs-20292R
英文名稱 TSPAN6 Rabbit pAb
中文名稱 四分子交聯(lián)體6抗體(四旋蛋白)
別    名 Putative NF kappa B activating protein 321; Putative NF-kappa-B-activating protein 321; T245; T245 protein; Tetraspan TM4SF; Tetraspanin 6; Tetraspanin TM4 D; Tetraspanin TM4-D; Tetraspanin TM4D; Tetraspanin-6; Tm4sf; TM4SF6; Transmembrane 4 superfamily member 6; TSN6_HUMAN; TSPAN 6; Tspan-6; TSPAN6; Tspan6 protein.  
研究領域 腫瘤  細胞生物  染色質和核信號  神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPAN6: 1-100/245 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. Members of the tetraspanin family are characterized by the presence of four hydrophobic domains and play a role in cell development, activation, growth and motility. TSPAN6 (tetraspanin-6), also known as A15 homolog, putative NF-kappa-B-activating protein 321, T245 protein, tetraspanin TM4-D or TM4SF6 (transmembrane 4 superfamily member 6), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. TSPAN6 is expressed at high levels in brain, with lower levels of expression found in colon, lung, pancreas, prostate, retina and melanocytes, as well as fetal heart, liver and spleen. The gene encoding TSPAN6 maps to the human X chromosome.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

SWISS:
O43657

Gene ID:
7105

Database links:

Entrez Gene: 7105 Human

Omim: 300191 Human

SwissProt: Q32KU6 Cow

SwissProt: O43657 Human

Unigene: 43233 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TSPAN6) Polyclonal Antibody, Unconjugated (bs-20292R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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