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Mouse IL-21 ELISA Kit (bsk12026)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
96T/2900.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bsk12026
英文名稱 Mouse IL-21 ELISA Kit
中文名稱 小鼠白細(xì)胞介素21酶聯(lián)免疫試劑盒
別    名 IL21; CVID11; IL-21; Za11; interleukin 21  
克 隆 號(hào)
種    屬 Mouse
線性范圍 31.25-2000 pg/mL
應(yīng)用范圍 S/P/CC
檢測(cè)限 16 pg/mL
適用樣品基質(zhì) cell culture supernates, serum, and plasma.
保存條件 Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.).
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells.This cytokine induces cell division/proliferation in its target cells.It has been shown that IL-21R knock-out mice express higher levels of IgE and lower levels of IgG1 than normal mice after antigen exposure. IgE levels decreased after mice were injected with IL-21. This has implications for the role of IL-21 in controlling allergic responses because of the role of IgE in hypersensitivity type 1 responses.IL-21 has been tried as therapy for alleviating allergic responses. It was shown to be successful in decreasing pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).A study using mice with peanut allergies showed that systemic treatment of IL-21 was an effective means of mitigating the allergic response.This has strong implications for the pharmacological development of IL-21 for controlling both localized and systemic allergies.

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