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Integrin Alpha V + Beta 5, BF680 conjugated (bs-1356R-BF680)  
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100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1356R-BF680
英文名稱 Integrin Alpha V + Beta 5, BF680 conjugated
中文名稱 BF680標(biāo)記的整合素αVβ5抗體
別    名 Integrin alpha 5 beta 5; alpha 5; alpha polypeptide; CD49e; CD51; fibronectin receptor; FNRA; Integrin alpha V; Integrin beta 5; ITGA5; ITGAV; ITGB5; VLA5A; VNRA.  
研究領(lǐng)域 細(xì)胞生物  干細(xì)胞  細(xì)胞粘附分子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 88/121kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.

Subcellular Location:
Cell Membrane

SWISS:
P06756

Gene ID:
3685

Database links:

Entrez Gene: 395142 Chicken

Entrez Gene: 396420 Chicken

Entrez Gene: 3685 Human

Entrez Gene: 3693 Human

Omim: 147561 Human

Omim: 193210 Human

SwissProt: P26008 Chicken

SwissProt: P06756 Human

SwissProt: P18084 Human

Unigene: 436873 Human

Unigene: 536663 Human



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