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GGNBP2 Rabbit pAb (bs-25128R)  
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50ul/1180.00元
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200ul/2800.00元
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產(chǎn)品編號(hào) bs-25128R
英文名稱 GGNBP2 Rabbit pAb
中文名稱 鋅指蛋白403/喉癌相關(guān)蛋白1抗體
別    名 DIF-3; DIF3; FLJ21230; FLJ22561; Gametogenetin-binding protein 2; GGNB2_HUMAN; Ggnbp2; Laryngeal carcinoma-related protein 1; LCRG1; LZK1; Protein ZNF403; ZFP403; ZNF403.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse,Rat (predicted: Human,Pig,Sheep,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:400-800,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GGNBP2: 501-600/697 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 LCRG1 is a 697 amino acid protein that may be involved in spermatogenesis. LCRG1 interacts with gametogenetin, a protein primarily expressed in testis and ovary. Localized in the cytoplasm, LCRG associates with vesicular structures. LCRG1 is expressed in brain, placenta, lung, liver and kidney, with highest levels found in heart, pancreas and skeletal muscle. LCRG1 is strongly down-regulated in 40% of primary laryngeal carcinoma and in 6 of 10 various cancer cell lines. Phosphorylated on Serine 360, LCRG1 exists as three isoforms produced by alternative splicing events.

Function:
May be involved in spermatogenesis.

Subcellular Location:
Cytoplasmic vesicle. Associated with vesicular structures.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed more abundantly in heart, pancreas and skeletal muscle.

SWISS:
Q9H3C7

Gene ID:
79893

Database links:

Entrez Gene: 79893 Human

Omim: 612275 Human

SwissProt: Q9H3C7 Human

Unigene: 514116 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GGNBP2) Polyclonal Antibody, Unconjugated (bs-25128R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GGNBP2) Polyclonal Antibody, Unconjugated (bs-25128R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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