亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久久久亚洲AV成人人电影,美女视频黄a视频全免费网站色窝
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
MUC2 Rabbit pAb (bs-60331R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1580.00元
100ul/2500.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-60331R
英文名稱(chēng) MUC2 Rabbit pAb
中文名稱(chēng) 粘蛋白-2/上皮膜抗原2抗體
別    名 MLP; SMUC; Intestinal mucin 2; MUC 2; MUC2; Mucin 2; Mucin 2 intestinal; Mucin 2 intestinal/tracheal; Mucin 2 oligomeric mucus/gel forming; Mucin 2 precursor; Mucin 2 tracheal; Mucin like protein; Intestinal mucin-2; MUC-2; MUC2_HUMAN; Mucin-2; Mucin2.  
Specific References  (2)     |     bs-60331R has been referenced in 2 publications.
[IF=5.561] Qianqian Yao. et al. The Milk Active Ingredient, 2′-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro. FOODS. 2023 Jan;12(1):186  IF ;  Human.  
[IF=3.337] Wang, Chengyao. et al. Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function. CELL MOL BIOENG. 2022 Sep;:1-12  IF ;  Human.  
研究領(lǐng)域 腫瘤  信號(hào)轉(zhuǎn)導(dǎo)  糖蛋白  細(xì)胞類(lèi)型標(biāo)志物  腫瘤細(xì)胞生物標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,ICC/IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 570 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MUC2 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Function:
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

Subunit:
Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP. Interacts with AGR2; disulfide-linked.

Subcellular Location:
Secreted. Note=In the intestine, secreted into the inner and outer mucus layers.

Tissue Specificity:
Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

Post-translational modifications:
O-glycosylated. May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the expanded volume and loose nature of this layer which allows for bacterial colonization in contrast to the inner mucus layer which is dense and devoid of bacteria. At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of the late secretory pathway.

Similarity:
Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 TIL (trypsin inhibitory-like) domain. Contains 2 VWFC domains.

SWISS:
Q02817

Gene ID:
4583

Database links:

Entrez Gene: 4583 Human

Entrez Gene: 17831 Mouse

Entrez Gene: 24572 Rat

SwissProt: Q02817 Human

SwissProt: Q80Z19 Mouse

SwissProt: Q62635 Rat



細(xì)胞粘附蛋白(Call Adhesion Protein)
上皮膜抗原是粘性糖蛋白家族之一,是一種膜內(nèi)在糖蛋白。Muc-2表達(dá)僅限于內(nèi)膜腺上皮和腔上皮,很多上皮細(xì)胞及其來(lái)源的腫瘤表達(dá)該蛋白.其合成和分泌是腺上皮組織的特征之一。MUC-2也是一種主要的腸道粘蛋白,在正常腸道和結(jié)腸癌、胃癌等腫瘤中有廣泛分布。該抗體主要用于胃腸道腫瘤的研究。
產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with MUC2 polyclonal antibody, unconjugated (bs-60331R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
Paraformaldehyde-fixed, paraffin embedded (Human duodenum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (MUC2) Polyclonal Antibody, Unconjugated (bs-60331R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (MUC2) Polyclonal Antibody, Unconjugated (bs-60331R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
精品福利一区二区三区免费视频 | 班长让我坐在那个地方教我作业 | rion美乳弹出来四虎在线观看 | 色欲精品久久人妻av中文字幕 | 综合一区二区自拍亚洲 | 国内毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片毛片 | 在线观看亚洲AV无码每日更新 | 国产精品亚欧美一区二区三区 | 日本国产一区二区三区 | 青青青免费高清在线观看一区二区 | 国产A级毛片久久久久久精品 | 国产V片在线播放免费无码 日韩在线视频一区二区三区 | 中文字幕亚洲综合小综合 | 日韩人妻无码精品久久a免费 | 色综合精品无码一区二区三区 | 娇喘嗯嗯~轻点啊视频福利 | 狠狠色丁香婷婷久久综合五月 | 六月婷婷国产精品综合 | 在线观看亚洲中文字幕 | 91精品一区二区三区在线观看 | 内射干少妇亚洲69XXX | 欲色aV无码一区二区人妻 | 牝教师4~秽された教坛~第6集 | 亚洲综合激情另类小说区 | 开心久久婷婷综合中文字幕 | 一级特黄特色的免费大片视频 | 久久强奷乱码老熟女 | 丰满白嫩尤物啪啪嗯啊动态图 | 最近中文字幕2018免费版2019 | VR虚拟专区亚洲精品二区 | 国产美女视频一区二区二三区 | 精品综合久久久久久88 | 国产精品宾馆精品酒店 | 国产成人综合久久精品免费欧美91 | 亚洲AV成人一区二区三区在线看 | 黄色一级片免费网站 | 91视频一区二区三区 | 色青青草原桃花久久综合 | 欧美精品18videose×性欧美 | 国产91在线视频观看 | 美女黄频视频大全免费的 |