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p38 MAPK Ready-To-Use IHC Kit (IHC0499)  
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50T/3200.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) IHC0499
英文名稱(chēng) p38 MAPK Ready-To-Use IHC Kit
中文名稱(chēng) p38 MAPK即用型免疫組化試劑盒
別    名 CRK1; CSBP; CSBP1; CSBP2; CSPB1; EXIP; Hog; MAPK14; MXI2; p38; p38-alpha; p38a; p38ALPHA; p38Hog; p38MAPK; PRKM14; PRKM15; RK; SAPK2A; Mxi2  
克 隆 號(hào)
適用樣品基質(zhì) FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
產(chǎn)品介紹 The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals. p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs. There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors. When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation. Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK. Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.

SWISS:
Q16539

Gene ID:
1432

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded mouse colon tissue slide using IHC0499 (p38 MAPK IHC Kit).
Immunohistochemical analysis of paraffin embedded human breast cancer tissue slide using IHC0499 (p38 MAPK IHC Kit).
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0499 (p38 MAPK IHC Kit).
Immunohistochemical analysis of paraffin embedded rat colon tissue slide using IHC0499 (p38 MAPK IHC Kit).
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