亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品成a人亚洲精品无码,国产亚洲欧美成人久久片,日韩欧美高清一区
Rabbit Anti-SFRP1/Cy3 Conjugated antibody (bs-1303R-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1303R-Cy3
英文名稱 Rabbit Anti-SFRP1/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的分泌型卷曲相關(guān)蛋白1抗體
別    名 Secreted frizzled related protein 1; Frizzled related protein 1; FRP 1; SARP 2; SARP-2; Secreted apoptosis related protein 2; Secreted Apoptosis-related Protein 2; Secreted frizzled related protein; Secreted Frizzled-related Protein 1; Secreted frizzled-related protein; SFRP 1; sFRP-1; SFRP1; SFRP1_HUMAN; SFRP1; FRP; FRP-1; FRP1; FrzA; SARP2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SFRP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]

Function:
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Subunit:
Interacts with WNT1, WNT2 and FRZD6. Interacts with WNT4 and WNT8.

Subcellular Location:
Secreted. Note=Cell membrane or extracellular matrix-associated. Released by heparin-binding.

Tissue Specificity:
Widely expressed. Absent from lung, liver and peripheral blood leukocytes. Highest levels in heart and fetal kidney. Also expressed in testis, ovary, fetal brain and lung, leiomyomal cells, myometrial cells and vascular smooth muscle cells. Expressed in foreskin fibroblasts and in keratinocytes.

Similarity:
Belongs to the secreted frizzled-related protein (sFRP) family.
Contains 1 FZ (frizzled) domain.
Contains 1 NTR domain.

Database links:

Entrez Gene: 6422 Human

Entrez Gene: 20377 Mouse

Omim: 604156 Human

SwissProt: Q8N474 Human

SwissProt: Q8C4U3 Mouse

Unigene: 213424 Human

Unigene: 281691 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

分泌型卷曲相關(guān)蛋白1是近來發(fā)現(xiàn)的新的抑癌基因, 是Wnt信號(hào)通道的拮抗通路蛋白,SFRP1能夠阻斷某些發(fā)生在癌癥初期與之相關(guān)的細(xì)胞生長(zhǎng)基因的信號(hào)通路。
有學(xué)者認(rèn)為:該基因有去甲基化酶的作用,可以阻斷與甲基化進(jìn)程相關(guān)酶的活性,進(jìn)而抑制腫瘤基因的改變,SFRP1的作用還有待于更進(jìn)一步的研究。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产A级毛片久久久久久精品 | 精品无码一区二区三区亚洲桃色 | 蜜桃网站入口可看18禁 | 国产伦精品一区二区三区免.费 | 国产精品亚洲AV毛片一区二区三区 | 国产精品色内内在线播放 | 欧美日韩一级久久久久久免费看 | 国产免费伦精品一区二区三区 | 国产精品高潮久久久久无码 | 使劲快高潮了国语对白在线 | 精品1区2区3区产品乱码 | 开心婷婷五月综合基地 | 成人做受120秒试看动态图 | 国内精品人妻色欲无码久久久 | 91精品免费久久久久久久久 | 中文字幕久久久久久一区二区三区 | 亚洲一区二区三区首页欧美 | 国产精品久久久久久久人热 | 适合晚上看的东西免费软件 | 国产乱老熟视频乱老熟女51 | 久久中文字幕亚洲精品最新 | 中国又粗又大又黄大片 | 中国亚洲女人69内射少妇 | 人妻体体内射精一区二区三区电影 | 66亚洲一卡2卡新区成片发布 | 成熟少妇大片免费看 | 成年入口无限观看免费完整大片 | AV无码播放一级毛片免费野外 | 欧美BBBBBBSBBBBBB| 漂亮人妻被强中文字幕 | 久久特级av一级毛片 | 国产成+人欧美+综合在线观看 | 无码精品人妻一区二区三区影院 | 亚洲中文字幕无码一久久区 | 伊人久久大香线蕉成人综合网 | 黑白配黑粗硬大疯狂乱叫 | 丰满老女人一级毛片视频 | 《久久国产91成人免费网站 | 综合人妻久久一区二区精品 | 91精品国产无码高清 | 欧美激情视频一区二区三区不卡 |