亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
熟女作爱一区二区视频,成全视频观看免费高清动漫,色婷婷综合激情中文在线
Rabbit Anti-CARD11/PE-Cy3 Conjugated antibody (bs-6201R-PE-Cy3)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-6201R-PE-Cy3
英文名稱(chēng) Rabbit Anti-CARD11/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的凋亡加強(qiáng)結(jié)構(gòu)域蛋白11抗體
別    名 Bcl10 interacting maguk protein 3; BIMP 3; BIMP3; CAR11_HUMAN; CARD 11; CARD containing MAGUK protein 3; Card maguk protein 1; CARD-containing MAGUK protein 1; CARD11; CARD11 protein; Carma 1; CARMA1; Caspase recruitment domain containing protein 11; Caspase recruitment domain family member 11; Caspase recruitment domain-containing protein 11; MGC133069.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  b-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CARD11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Function:
Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Subunit:
Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. CARD11 and BCL10 bind to each other by CARD-CARD interaction. Interacts (via PDZ domain) with DPP4 (via cytoplasmic tail).

Subcellular Location:
Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.

Tissue Specificity:
Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells.

Post-translational modifications:
Phosphorylation at Ser-559, Ser-644 and Ser-652 by PRKCB and PRKCQ leads to a shift from an inactive to an active form that activates the NF-kappa-B signaling

Similarity:
Contains 1 CARD domain.
Contains 1 guanylate kinase-like domain.
Contains 1 PDZ (DHR) domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产AV国片精品一区二区 | 国产欧美日韩高清在线不卡 | 国产精品一国产AV麻豆 | 男男被一根又一根H强迫NP | 日本那些又骚又爽的视频 | 亚洲调教自慰喷水AV无码 | 最近免费中文字幕MV免费高清 | AV片在线观看免费光看高清 | 色婷婷综合激情中文在线 | 久久国产精品高潮一级毛片 | 亚洲欧美激情精品一区二区 | 成年香蕉大黄美女美女 | 国产欧美日韩高清在线不卡 | 亚洲日本久久久午夜精品 | 欧美日韩精品一区二区三区不卡 | 日韩高清免费视频观看 | 正在播放国产Av国模私拍 | 未满十八18禁止免费无码网站 | 久久久久亚洲女同一区二区 | 麻豆传播媒体免费版官网 | 免费无码又爽又黄又刺激网站 | 激情射精爽到偷偷C视频无码 | 神马免费午夜福利剧场 | 女人高潮久久久叫人喷水 | 性欧美video另类hd亚洲人 | 日韩一区精品视频一区二区 | 久久爱影院久久99久国产 | 人人妻人人澡人人爽国产一区 | 天堂网资源中文最新版 | 国产精品看片在线观看 | 亚洲乱妇老熟女爽到高潮的片 | 扒开腿挺进湿润的花苞 | 国内老熟妇对白HDXXXX | 韩国日本免费高清观看网址 | 丁香婷婷色五月激情综合深爱 | 国产又爽又黄无码无遮挡在线观看 | 日韩精品欧美视频 | 国产又大又硬又粗 | 狠狠色丁香婷婷综合尤物 | 成 人 免 费 黄 色 网站无毒下载 | 亚洲AV鲁丝一区二区三区 |