亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
韩国美女丝袜一区二区,精品无码国产污污污在线观看
Rabbit Anti-CARD11/BF488 Conjugated antibody (bs-6201R-BF488)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6201R-BF488
英文名稱 Rabbit Anti-CARD11/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的凋亡加強(qiáng)結(jié)構(gòu)域蛋白11抗體
別    名 Bcl10 interacting maguk protein 3; BIMP 3; BIMP3; CAR11_HUMAN; CARD 11; CARD containing MAGUK protein 3; Card maguk protein 1; CARD-containing MAGUK protein 1; CARD11; CARD11 protein; Carma 1; CARMA1; Caspase recruitment domain containing protein 11; Caspase recruitment domain family member 11; Caspase recruitment domain-containing protein 11; MGC133069.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  b-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CARD11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Function:
Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Subunit:
Found in a membrane raft complex, at least composed of BCL10, CARD11, DPP4 and IKBKB. CARD11 and BCL10 bind to each other by CARD-CARD interaction. Interacts (via PDZ domain) with DPP4 (via cytoplasmic tail).

Subcellular Location:
Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.

Tissue Specificity:
Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells.

Post-translational modifications:
Phosphorylation at Ser-559, Ser-644 and Ser-652 by PRKCB and PRKCQ leads to a shift from an inactive to an active form that activates the NF-kappa-B signaling

Similarity:
Contains 1 CARD domain.
Contains 1 guanylate kinase-like domain.
Contains 1 PDZ (DHR) domain.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产精品白浆无码流出AV动漫 | 色欲av无码一区二区人妻精油 | 91精品国产无码高清 | 秋葵视频ios无限制解码免费版下载 | 三级在线看中文字幕完整版 | 牝教师4~秽された教坛~第6集 | 18禁黄久久久AAA片 | 少妇荡乳情欲办公室456视频 | 蜜桃一区二区三区视频网址 | a毛片免费全部播放无风险 www.一级毛片 | 精品一区二区三区高清免费观看 | 真人短片20分钟以上 | 一区二区视频在线观看高清视频在线 | 国产精品久久免费视频 | 国产的一级毛片最新在线直播 | ▓成人榴莲视频▓无码免费 | 欧美午夜精品久久久久久浪潮 | 2021亚洲无码视频 | 午夜亚洲乱码伦小说区69堂 | 动漫精品中文无码卡通动漫 | 日韩精品久久久肉伦网站 | 粉嫩METART人体欣赏 | 免费无遮挡无码视频在线观看洗澡 | 久久久高清国产999尤物 | 久久成人国产精品免费 | 在线综合亚洲欧美网站无弹窗 | 亚洲 校园 欧美 国产 另类 | 欧美一级特黄乱妇高清视频 | 国产亚洲精品无码专区不卡 | 国产午夜影视大全免费观看 | 人与ZO00 视频 | 久久久久久曰本av免费免费 | 日本VS亚洲VS韩国一区三区四区 | 成人3d动漫在线观看网站 | 成熟丰满女人免费视频 | 亚洲AV综合色一区二区三区 | 80年代十大欧美成人片 | 欧美人与拘牲交大全O人禾 天天躁日日躁狠狠躁日日躁黑人 | 又黄又湿免费高清视频 | 久久精品国产a真人一级无码毛片一区二区 | 精品国产人成亚洲区 |