亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91青青国产在线观看免费,无码AV动漫精品一区二区免费,精品91网站在线观看
Rabbit Anti-Estrogen Related Receptor gamma/BF555 Conjugated antibody (bs-6213R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6213R-BF555
英文名稱 Rabbit Anti-Estrogen Related Receptor gamma/BF555 Conjugated antibody
中文名稱 BF555標(biāo)記的雌激素受體相關(guān)蛋白3抗體
別    名 ERR 3; ERR G2; ERR gamma 2; ERR gamma-2; ERR3; ERR3_HUMAN; ERRG 2; ERRG2; ESRRG; Estrogen receptor related protein 3; Estrogen receptor-related protein 3; Estrogen-related receptor gamma; NR3B3; Nuclear receptor subfamily 3 group B member 3.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.

Function:
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements

Subunit:
Homodimer. Binds TLE1, PNRC1 and PNRC2. Binds GRIP1 (By similarity). Interacts with NRIP1, NCOA1 and NCOR2.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.

Post-translational modifications:
Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.

Similarity:
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 536732 Cow

Entrez Gene: 2104 Human

Entrez Gene: 26381 Mouse

Entrez Gene: 360896 Rat

Entrez Gene: 405890 Zebrafish

Omim: 602969 Human

SwissProt: P62508 Human

SwissProt: P62509 Mouse

SwissProt: P62510 Rat

Unigene: 444225 Human

Unigene: 388156 Mouse

Unigene: 89989 Mouse

Unigene: 214491 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产AVXXXX无套内射 | 性一交一无一伦一精一爆 | 精品亚洲一区二区在线播放 | 精品国产一区二区三区AV性色 | 久久久久久高清毛片一级黑人免费 | 日韩一区二区免费视频 | 国产无吗一区二区三区在线欢 | 999精品视频这里只有精品 | 中文字幕一区二区日韩欧美 | 欧美大屁股XXXX高跟欧美黑人 | 蹂躏清冷仙子翘臀雪乳 | 特级av一级毛片乱中年女人伦 | 欧美乱码精品一区二区三区卡 | 女人和拘做受全过程免费 | 亚洲一区精品在线 | 久久91亚洲精品中文字幕 | 久久婷婷品香蕉频线观2021 | 黄色链接在线观看 | 国产精品99久久久精品无码 | 无码毛片内射白浆视频 | 国内精品一级毛片免费看 | 久久久久国产精品夜夜夜夜夜 | 国产无吗一区二区三区在线欢 | 夜鲁夜鲁很鲁在线视频视频 | 九九视频精品全部免费播放 | 久99久热只有精品国产女同 | 国产成人在线播放 | 成人无遮挡免费网站视频在线观看 | 久久国产精品免费观看 | 99国精品午夜福利视频不卡 | 欧美日韩激情无码专区 | 国产无遮挡又黄又爽在线视频 | 九九热这里只有国产精品 | 纯肉高H肉辣浪荡NP论J | 在线观看无码的免费网站 | 国产成人精品无缓存在线播放 | 美女用震蛋叫爽的视频95视频 | 五月的丁香六月的婷婷免费无毒不卡 | 欧美大片AAAAA免费观看 | 免费国产一级片内射视频 | 国产色综合色产在线视频 |