亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
免费久久99精品国产自在现,亚洲精品国产不卡在线观看,亚洲最大的视频网站
Rabbit Anti-Estrogen Related Receptor gamma/BF647 Conjugated antibody (bs-6213R-BF647)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6213R-BF647
英文名稱 Rabbit Anti-Estrogen Related Receptor gamma/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的雌激素受體相關(guān)蛋白3抗體
別    名 ERR 3; ERR G2; ERR gamma 2; ERR gamma-2; ERR3; ERR3_HUMAN; ERRG 2; ERRG2; ESRRG; Estrogen receptor related protein 3; Estrogen receptor-related protein 3; Estrogen-related receptor gamma; NR3B3; Nuclear receptor subfamily 3 group B member 3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ESRRG/Estrogen Related Receptor gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.

Function:
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements

Subunit:
Homodimer. Binds TLE1, PNRC1 and PNRC2. Binds GRIP1 (By similarity). Interacts with NRIP1, NCOA1 and NCOR2.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland.

Post-translational modifications:
Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity.
Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity.

Similarity:
Belongs to the nuclear hormone receptor family. NR3 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 536732 Cow

Entrez Gene: 2104 Human

Entrez Gene: 26381 Mouse

Entrez Gene: 360896 Rat

Entrez Gene: 405890 Zebrafish

Omim: 602969 Human

SwissProt: P62508 Human

SwissProt: P62509 Mouse

SwissProt: P62510 Rat

Unigene: 444225 Human

Unigene: 388156 Mouse

Unigene: 89989 Mouse

Unigene: 214491 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产综合成人久久大片91 | 国产精品视频一区二区猎奇 | 国产精品久久久久无码AV色戒 | 在线观看黄色视频网站 | 91人人人玩人人妻精品99 | 国产精品亚洲av综合成久久久久久三级 | 亚洲一区在线播放 | 91免费精品国自产拍在线可以看 | 最近中文字幕大全在线电影视频 | 国产欧美精品一区二区色综合 | 亚洲欧美乱日韩乱国产 | 4399视频免费观看大全 | 精品日韩乱码久久久久久 | 日本那些又骚又爽的视频 | 向日葵视频APP秋葵榴莲在线 | 少妇内射高潮福利炮 | 国产变态拳头交视频免费播放 | 夜夜爽妓女8888888视频 | 91精品一区二区三区在线观看 | 一二三区精品国产91久久久 | 在线看片免费人成视频电影sM | 性xxxxbbbb免费播放视频 | 欧美日韩视频一视频二视频三 | 人妻熟妇久久久久久精品无码 | 精品一卡2卡三卡4卡乱码毛1 | 日本精品一区二区三区在线 | 免费无码又爽又刺激网站直播 | 国内精品51视频在线观看 | 内射无码AV-区二区在线观看 | 中文字幕人妻紧无码专区 | 久久国产精品99久久久久久老狼 | 2024AV天堂手机在线观看 | 色av综合av综合无码网站 | 欧美又大粗又爽又黄大片视频 | 嗯好湿用力的啊c进来动态图 | 男女免费观看在线爽爽爽视频 | jizz国产丝袜18老师美女 | 伊人99综合精品视频 | 亚洲色熟女图激情另类图区 | 午夜精品久久久久久影视riav | 91av视频在线观看 |