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Rabbit Anti-SSTR3/BF488 Conjugated antibody (bs-1368R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-1368R-BF488
英文名稱 Rabbit Anti-SSTR3/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的生長抑素受體3抗體
別    名 somatostatin receptor 3; OTTHUMP00000028737; Smstr3; Somatostatin receptor 3; Somatostatin receptor subtype 3; Smstr 3; SS 3R; SS-3-R; SS3-R; SSR-28; SSR3_HUMAN; Sst3; SSTR 3; Somatostatin receptor type 3; SS3R; SSR28; Sst3; SSTR 3; SSTR3.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SSTR3 C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation.

Tissue Specificity:
Brain, pituitary and pancreas.

Post-translational modifications:
Phosphorylated. Phosphorylation increases upon somatostatin binding.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 6753 Human

Omim: 182453 Human

SwissProt: P32745 Human

Unigene: 225995 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

是一種連接G-蛋白的受體,主要分布在腦和胰腺。目前有學(xué)者用于腫瘤方面的研究。
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