亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
人妻少妇看A偷人无码电影,日本精品一区二区三区在线,国产91视频观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-BST2/RBITC Conjugated antibody (bs-9850R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9850R-RBITC
英文名稱 Rabbit Anti-BST2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的骨髓基質干細胞抗原2抗體
別    名 Bone marrow stromal antigen 2; Bone marrow stromal cell antigen 2; Bone marrow stromal cell antigen; BST 2; BST-2; BST2; BST2_HUMAN; CD 317; CD317; CD317 antigen; HM1.24 antigen; NPC A 7; Tetherin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  細胞生物  免疫學  干細胞  細胞表面分子  細胞類型標志物  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BST2/CD317
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Bone marrow stromal cells act as regulators for B-cell growth and development through their surface molecules and cytokines. Bone marrow stromal antigen-2 (BST-2), also designated CD317 antigen, is a single- pass type II membrane protein. BST-2, which is expressed mainly on synovial cell lines and bone marrow stromal cell lines, is primarily expressed in liver, heart, placenta and lung tissues. BST-2 is thought to be involved in pre-B cell growth. It has been implicated in B cell activation in rheumatoid arthritis.

Function:
IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), simian immunodeficiency viruses (SIVs), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), prototype foamy virus (PFV), Mason-Pfizer monkey virus (MPMV), human T-cell leukemia virus type 1 (HTLV-1), Rous sarcoma virus (RSV) and murine leukemia virus (MLV), flavivirideae: hepatitis C virus (HCV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), arenaviridae: lassa virus (LASV) and machupo virus (MACV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), rhabdoviridae: vesicular stomatitis virus (VSV), orthomyxoviridae: influenza A virus, and paramyxoviridae: nipah virus. Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.

Subunit:
Parallel homodimer; disulfide-linked. May form homotetramers under reducing conditions. Dimerization is essential for its antiviral activity. Interacts (via cytoplasmic domain) with ARHGAP44 (By similarity). Interacts with MMP14 (via C-terminal cytoplasmic tail). Interacts with LILRA4/ILT7. Interacts (via transmembrane domain) with HIV-1 VPU (via transmembrane domain). Interacts with HIV-2 ENV and ebola GP protein.

Subcellular Location:
Golgi apparatus; trans-Golgi network. Cell membrane. Cell membrane. Late endosome. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. Targeted to the trans-Golgi network by viral VPU protein.

Tissue Specificity:
Predominantly expressed in liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal muscle and brain. Overexpressed in multiple myeloma cells. Highly expressed during B-cell development, from pro-B precursors to plasma cells. Highly expressed on T-cells, monocytes, NK cells and dendritic cells (at protein level).

Post-translational modifications:
Monoubiquitinated by KSHV E3 ubiquitin-protein ligase K5, leading to its targeting to late endosomes and degradation.
The GPI anchor is essential for its antiviral activity.

Similarity:
Belongs to the tetherin family.

Database links:

Entrez Gene: 684 Human

Omim: 600534 Human

SwissProt: Q10589 Human

Unigene: 118110 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
抽插黄文NP合欢宗 | 亚洲伊人久久综合影院2021 | 免费在线观看的毛片 | 国产日产亚洲系列最新美使用方法 | 国产超碰人人模人人爽人人添 | 中文字幕一级毛片无码视频 | 欧美精品一本久久男人的天堂 | 国第一产在线精品亚洲区^& | 情侣网站大黄网站 | 麻豆精品久久久一区二区 | 91桃色污无限免费看 | 色婷婷AV一区二区三区在线观看 | 国产精品久久久久无码AV | 尤物99在线视频观看 | 国产一区二区三区影院 | 男女牲交全程播放免费 | 97人人超碰国产精品最新 | 久久成人无码国产免费播放 | 欧美.日韩.日本国产视频 | 日本不卡一区二区三区 | 国产99久久久国产精品潘金莲 | 又粗又硬大战丰满少妇柔 | 免费无遮挡无码视频在线观看洗澡 | 国产成人一区免费观看 | 18禁国产精品久久久久久久久 | 中国国语毛片免费观看视频 | 蜜桃羞羞小视频在线观看 | 亚洲色大成网站WWW永久 | 国产精品自慰在线观看 | 豪妇荡乳1一5白玉兰免费下载 | 人妻无码精品蜜桃HD91精品国产 | 综合久久狠狠色99h中午 | 国产中文字幕久久精品网址 | 无码高潮喷水在线播放观看 | 欧美亚洲日本一区二区三区浪人 | 波多野结衣av一区二区全免费观看 | 麻豆传播媒体免费版官网 | 18禁止看的免费污网站 | 被CAO哭高H野外NP小说男男 | 色婷婷色综合缴情网站 | 熟女少妇内射日韩亚洲 |