亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产内射爽爽大片视频社区在线,久久香蕉综合一本到3atv,国产午夜精品喷水久久
Rabbit Anti-Doublecortin/BF594 Conjugated antibody (bs-1269R-BF594)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-1269R-BF594
英文名稱(chēng) Rabbit Anti-Doublecortin/BF594 Conjugated antibody
中文名稱(chēng) BF594標(biāo)記的雙皮質(zhì)素抗體
別    名 Doublecortex; DBCN; Dbct; DC; DCX; Doublin; Lis X; Lissencephalin X; Lissencephaly X linked; Lissencephaly X linked doublecortin; LISX; Neuronal migration protein doublecortin; SCLH; XLIS.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞粘附分子  細(xì)胞類(lèi)型標(biāo)志物  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Chicken, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Doublecortin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Neuronal Marker

Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express, a marker for mature neurons. Due to the nearly exclusive expression of DCX in developing neurons, this protein has been used increasingly as a marker for neurogenesis. Indeed, the levels of DCX expression increase in response to exercise, which occurs in parallel with increased BrdU labelling, currently a "gold standard" in measuring neurogenesis.

Function:
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration.

Subunit:
Interacts with tubulin.

Subcellular Location:
Cytoplasm. Cell projection. Note=Localizes at neurite tips.

Tissue Specificity:
Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.

Post-translational modifications:
Phosphorylation by MARK1, MARK2 and PKA regulates its ability to bind mirotubules.

DISEASE:
Defects in DCX are the cause of lissencephaly X-linked type 1 (LISX1) [MIM:300067]; also called X-LIS or LIS. LISX1 is a classic lissencephaly characterized by mental retardation and seizures that are more severe in male patients. Affected boys show an abnormally thick cortex with absent or severely reduced gyri. Clinical manifestations include feeding problems, abnormal muscular tone, seizures and severe to profound psychomotor retardation. Female patients display a less severe phenotype referred to as 'doublecortex'.
Defects in DCX are the cause of subcortical band heterotopia X-linked (SBHX) [MIM:300067]; also known as double cortex or subcortical laminar heterotopia (SCLH). SBHX is a mild brain malformation of the lissencephaly spectrum. It is characterized by bilateral and symmetric plates or bands of gray matter found in the central white matter between the cortex and cerebral ventricles, cerebral convolutions usually appearing normal.
Note=A chromosomal aberration involving DCX is found in lissencephaly. Translocation t(X;2)(q22.3;p25.1).

Similarity:
Contains 2 doublecortin domains.

Database links:

Entrez Gene: 1641 Human

Entrez Gene: 13193 Mouse

Entrez Gene: 84394 Rat

Omim: 300121 Human

SwissProt: O43602 Human

SwissProt: O88809 Mouse

SwissProt: Q9ESI7 Rat

Unigene: 34780 Human

Unigene: 12871 Mouse

Unigene: 121471 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神經(jīng)細(xì)胞標(biāo)志物(Neuronal Marker)
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
特级毛片内射WWW无码 | 久久婷婷品香蕉频线观2021 | 特级做a爰片毛片免费看 | 丝袜精品人妻自慰喷白浆一区 | 久久强奷乱码老熟女网站 | 国产一区二区三区内射高清 | 日韩成人在线视频 | 屁屁国产第1页草草影院 | 国产又黄又爽无遮挡动态图 | 久久久精品久久久久久久久久久 | 国产91精品太粉嫩高中在线观看 | 国产99在线a视频 | 精品久久BBBBB精品人妻 | 国产亚洲精品精品精品 | 欧美人妻中文字幕乱码在线 | 国产成人精选视频在线观看不卡 | q2002午夜我的老师 | 青青草国产免费一区二区 | 国产欧美在线播放 | 亚洲综合另类一区无码 | ▓成人榴莲视频▓无码免费 | 善良娇妻在老汉跨下呻吟 | 欧美日韩人妻精品一区在线 | 国产精品系列在线观看 | 中文字幕一区中文亚洲 | 亚洲成A人片在线播放 | 福利一区二区视频 | 亚洲日本一线产区和二线产 | 亚洲乱码日产精品BD在线看 | 亚洲国产精品久久久久秋霞小 | 亚洲国产系列一区二区三区 | 久久久又黄又爽免费观看下载 | 日韩成人大屁股内射喷水 | 一个人免费观看视频www | 最近中文字幕完整视频大全 | 日韩精品一区二区三区中文不卡 | 老师好大乳好紧好深动态图 | 日本免费一级婬片A级中文字幕 | 超级乱淫小黄文小说 | 亚洲国产精品剧情污污 | 91精品国产色综合久久不卡美美 |