亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美成人免费高清二区三区,亚洲色婷婷久久99精品91,我两腿被同学摸的直流水
Rabbit Anti-RAP1A/BF555 Conjugated antibody (bs-1504R-BF555)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1504R-BF555
英文名稱(chēng) Rabbit Anti-RAP1A/BF555 Conjugated antibody
中文名稱(chēng) BF555標(biāo)記的Rap1A抗體
別    名 C21KG; RAP1; G 22K; G-22K; GTP binding protein smg p21A; GTP-binding protein smg p21A; KREV 1; KREV-1; KREV1; OTTHUMP00000013741; RAP 1A; RAP1; RAP1A; RAP1A member of RAS oncogene family; RAP1A_HUMAN; Ras related protein Krev 1; Ras related protein Rap 1A; RAS related protein RAP1A; Ras-related protein Krev-1; Ras-related protein Rap-1A; SMGP21; rap1a; RAS-related protein-1a precursor; Rap1A-retro2; RAP1A, member of RAS oncogene family.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Chicken, Cow, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RAP1A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].

Function:
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.

Subunit:
Found in a complex, at least composed of ITGB1BP1, KRIT1 and RAP1A. Interacts (active GTP-bound form preferentially) with KRIT1 (via C-terminus FERM domain); the interaction does not induce the opening conformation of KRIT1. In its GTP-bound form interacts with PLCE1 and RADIL. Interacts with SGSM1, SGSM2 and SGSM3. Interacts (via GTP-bound active form) with RAPGEF2 (via Ras-associating domain)

Subcellular Location:
Cell membrane; Lipid-anchor. Cytoplasm. Cytoplasm, perinuclear region. Cell junction. Early endosome. Note=Recruited from early endosome to late endosome compartment after nerve growth factor (NGF) stimulation. Localized with RAPGEF2 at cell-cell junctions. Colocalized with RAPGEF2 in the perinuclear region.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

Database links:

Entrez Gene: 5906 Human

Entrez Gene: 109905 Mouse

Entrez Gene: 295347 Rat

Omim: 179520 Human

SwissProt: P62834 Human

SwissProt: P62835 Mouse

SwissProt: P62836 Rat

Unigene: 190334 Human

Unigene: 458171 Mouse

Unigene: 106321 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

RAP1A 是RAS癌基因家族成員,在調(diào)節(jié)細(xì)胞增生和粘附中有重要作用.經(jīng)研究發(fā)現(xiàn),Rap1和它的調(diào)節(jié)子SPA-1在很多惡性腫瘤的發(fā)生、發(fā)展中起到一定的作用。定位于胞漿、胞膜。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产女主播喷水视频在线观看 | 偷拍激情视频一区二区三区 | 国产99久久久国产精品潘金莲 | 一本大道香蕉青青久久 | 综合久久国产九一剧情麻豆 | 日本午夜精品一区二区三区电影 | 日本特级婬片a片免费手机版 | WWW.啪啪小白浆内射无码 | 99热门精品一区二区 | 亚洲第一成年人网站 | 亚洲无线一二三四区手机 | 婷婷色婷婷开心五月四房播播久久 | 久久久久久成人毛片免费看 | 成人国产射精AV在线 | 黄色网站在线观看免费 | 免费在线看一级黄色网站 | 精品日本亚洲一区二区三区 | 欧美精品人人做天天操夜夜操 | 欧美激情视频在线观看一区二区三区 | 国产精品日韩欧美一区二区三区 | 草莓黄瓜蜜桃视频app下载 | 动漫精品视频一区二区三区 | 公与淑婷厨房猛烈进出视频韩国 | 国产精品户露AV在线户外直播 | 国产亚洲成AⅤ人片在线观看 | 手机在线毛片免费播放 | 久久精品视频91 | 99狠狠噜夜夜澡人人爽人人爽 | 国产99久久亚洲综合精品 | 国产真人无码作爱视频 | 欧美一级高清AAA片免费观看 | 国产成A人亚洲精V品无码樱花 | 大又大又粗又硬又爽少妇毛片 | 最近中文字幕大全在线电影视频 | 国产乱码精品一区二区三区四川 | 亚洲国产精品一区二区动图 | 最近免费中文字幕大全高清大全10 | 天堂8在线天堂资源BT | 一本精品99久久精品66不卡婷婷 | 午夜福利一区二区三区在线观看 | 久久免费看少妇高潮喷水 |