亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
国产黄色网站在线观看,内射中出无码护士在线
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-phospho-cardiac Troponin I (Thr143)/BF555 Conjugated antibody (bs-9860R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9860R-BF555
英文名稱 Rabbit Anti-phospho-cardiac Troponin I (Thr143)/BF555 Conjugated antibody
中文名稱 BF555標記的磷酸化心肌肌鈣蛋白抗體
別    名 cardiac Troponin I (phospho Thr143); p-cardiac Troponin I (Thr143); cardiac Troponin I (phospho T143); p-cardiac Troponin I (T143); Cardiac troponin I; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; p-Tn1; p-Tni; TNN I3; p-TNNC 1; p-TNNC1; p-TNNI3; p-Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; TNNI3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領域 心血管  信號轉(zhuǎn)導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human cardiac Troponin I around the phosphorylation site of Thr143
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

Function:
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Subunit:
Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1.

Post-translational modifications:
Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction. Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).

DISEASE:
Defects in TNNI3 are the cause of familial hypertrophic cardiomyopathy type 7 (CMH7) [MIM:613690]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Defects in TNNI3 are the cause of familial restrictive cardiomyopathy type 1 (RCM1) [MIM:115210]. RCM1 is a heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 1FF (CMD1FF) [MIM:613286]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Similarity:
Belongs to the troponin I family.

Database links:

Entrez Gene: 7137 Human

Entrez Gene: 21954 Mouse

Entrez Gene: 100049696 Pig

Entrez Gene: 29248 Rat

Omim: 191044 Human

SwissProt: P19429 Human

SwissProt: P48787 Mouse

SwissProt: P23693 Rat

Unigene: 709179 Human

Unigene: 27674 Mouse

Unigene: 64141 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

心肌肌鈣蛋白(Cardiac Troponin CTn1)是心肌收縮的調(diào)節(jié)蛋白,存在于心肌收縮蛋白的細肌絲上。肌鈣蛋白的作用之一是把原肌凝蛋白(Tropomyosin.Tm)附著于肌動蛋白(Action.A)上、 主要用于心肌功能方面的研究。
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产AV国内精品JK制服 | 东北少妇不戴套对白第一次 | 99热99re8国产在线播放 | 五月天精品视频在线观看 | 久久爱影院久久99久国产 | 国产在线观看不卡 | 日韩精品视频美在线精品视频 | 第九色区av天堂 | 不卡高清AV手机在线观看 | 最近日本字幕MV高清在线观看 | 一区二区高清无码电影 | 欧美高清视频www夜色资源网 | 国产黄a一级二级三级看三区 | 榴莲视频在线看一日韩 | 欧美日韩无套内射另类 | 久久久久成人精品无码国产一区 | 欧美人成国产91视频 | 国产2021中文天码字幕 | 久久久高清国产999尤物 | 欧美午夜精选久久久A | 曰韩无码一区二区三区 | 日韩成人大屁股内射喷水 | 强奸伦久久久久久久久久久特级av | 国产精品99久久久久久宅男小说 | 无码A∨高潮抽搐流白浆国产 | 免费国产黄网站在线观看可以下载 | 免费国产成人高清在线视频 | 五十丰满熟妇性旺盛 | 无码狠狠躁久久久久久久 | 免费永久在线观看黄网 | 爱爱好爽好大好紧视频 | 男女上下抽搐~嗯~啊~ | 国产黄在线观看免费观看不卡 | 日韩成人电影在线观看 | 欧美久久一级内射wwwwww. | 国产真人无遮挡作爱免费视频 | 国产欧美日本在线 | 国产69精品久久久久无码小说 | 51国偷自产一区二区三区 | 女人高潮久久久叫人喷水 | 国产国语高清在线视频二区 |