亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91久久综合精品国产丝袜长腿,边做饭边被躁在线播放
Rabbit Anti-phospho-cardiac Troponin I (Thr143)/BF594 Conjugated antibody (bs-9860R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9860R-BF594
英文名稱 Rabbit Anti-phospho-cardiac Troponin I (Thr143)/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的磷酸化心肌肌鈣蛋白抗體
別    名 cardiac Troponin I (phospho Thr143); p-cardiac Troponin I (Thr143); cardiac Troponin I (phospho T143); p-cardiac Troponin I (T143); Cardiac troponin I; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; p-Tn1; p-Tni; TNN I3; p-TNNC 1; p-TNNC1; p-TNNI3; p-Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; TNNI3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 心血管  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24 kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human cardiac Troponin I around the phosphorylation site of Thr143
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

Function:
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Subunit:
Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1.

Post-translational modifications:
Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction. Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T).

DISEASE:
Defects in TNNI3 are the cause of familial hypertrophic cardiomyopathy type 7 (CMH7) [MIM:613690]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
Defects in TNNI3 are the cause of familial restrictive cardiomyopathy type 1 (RCM1) [MIM:115210]. RCM1 is a heart muscle disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 2A (CMD2A) [MIM:611880]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Defects in TNNI3 are the cause of cardiomyopathy dilated type 1FF (CMD1FF) [MIM:613286]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Similarity:
Belongs to the troponin I family.

Database links:

Entrez Gene: 7137 Human

Entrez Gene: 21954 Mouse

Entrez Gene: 100049696 Pig

Entrez Gene: 29248 Rat

Omim: 191044 Human

SwissProt: P19429 Human

SwissProt: P48787 Mouse

SwissProt: P23693 Rat

Unigene: 709179 Human

Unigene: 27674 Mouse

Unigene: 64141 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

心肌肌鈣蛋白(Cardiac Troponin CTn1)是心肌收縮的調(diào)節(jié)蛋白,存在于心肌收縮蛋白的細(xì)肌絲上。肌鈣蛋白的作用之一是把原肌凝蛋白(Tropomyosin.Tm)附著于肌動(dòng)蛋白(Action.A)上、 主要用于心肌功能方面的研究。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
丰满少妇被猛烈进入毛片 | 懂色aⅴ一区二区三区免费 高潮毛片无遮挡高清免费视频 | 国产国语高清在线视频二区 | 亚洲一区欧洲一区 | 欧美一区二区视频在线观看 | 特级做a爰片毛片免费看 | 欧美亚洲另类热图 | 999久久狠狠免费精品 | 成人午夜黄网站在线观看 | 国产精品亚洲av综合成久久久久久三级 | 日韩精品福利视频一区二区三区 | 国产免费成人在线视频 | 国产男人午夜视频在线观看 | 曰本a∨久久综合久久 | 亚洲日本香蕉视频观看视频 | 永久免费A片在线观看无码 免费一级A片毛毛片在线播放99 | 中国国语毛片免费观看视频 | 成人黄网站 免费视频 | 国产综合无码一区二区色蜜蜜 | 久久婷婷五月综合丁香人人爽 | 午夜精品一区二区三区在线观看 | 欧美一级又粗又大真做 | 特级做a爰片毛片免费69 | 在线天堂新版最新版在线8 а√在线中文网新版地址在线 | 亚洲AV无码一区二区三区在线高 | 欧美日韩国产综合视频在线观看 | 久久久无码人妻精品无码 | 国语的ZOOFILIA杂交VIDEOS新 | 丰满妇女BBWBBWBBWBBW | 久久久91精品国产一区二区 | 农村女人一级毛片20岁的毛片 | 精品一区二区三区高清免费观看 | 久久www免费人成高清 | 国产精品人人爽人人做Av片 | 在线高清国语成人网站 | 天天综合网网欲色 | 91久久精品美女高潮喷水白浆 | 亚洲欧美卡通动漫丝袜 | 亚欧精品一区二区三区四区 | 国产精品久久国产三级国电话系列 | 亚色九九九全国免费视频 |