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Rabbit Anti-LI Cadherin/BF594 Conjugated antibody (bs-1617R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1617R-BF594
英文名稱 Rabbit Anti-LI Cadherin/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的肝腸鈣粘連蛋白抗體
別    名 BILL-cadherin; LI-cadherin; CAD17_HUMAN; Cadherin 16; Cadherin 16, formerly; Cadherin 17; cadherin 17, LI cadherin (liver-intestine); cadherin, liver-intestine; Cadherin-17; CDH16; CDH16, formerly; Cdh17; FLJ26931; Formerly Cadherin 16; Formerly CDH16; HPT 1; HPT-1 cadherin; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; Intestinal peptide-associated transporter HPT 1; Intestinal peptide-associated transporter HPT-1; LI-cadherin; Liver Cadherin; liver intestine cadherin; Liver-intestine cadherin.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LI-cadherin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Potential).

Tissue Specificity:
Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.

Similarity:
Contains 7 cadherin domains.

Database links:

Entrez Gene: 1015 Human

Omim: 603017 Human

SwissProt: Q12864 Human

Unigene: 591853 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肝腸鈣粘連蛋白是鈣粘連蛋白超家族中的特殊一員,在結(jié)構(gòu)上與經(jīng)典Ⅰ型鈣粘連蛋白有所不同而被劃分為經(jīng)典鈣粘連蛋白的變異體,主要用于消化道腫瘤方面的研究。
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