亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
在线天堂新版最新版在线8,国产日韩精品一区二区三区在线,最近中文字幕国语免费高清6
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-XBP1/Cy7 Conjugated antibody (bs-1668R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1668R-Cy7
英文名稱 Rabbit Anti-XBP1/Cy7 Conjugated antibody
中文名稱 Cy7標記的細胞核轉(zhuǎn)錄因子X盒結合蛋白抗體
別    名 X box-binding protein-1; XBP-1; XBP1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; X-box-binding protein 1 in isoform 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Cow, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29/40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human XBP-1 (51-90aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]

Function:
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Subcellular Location:
Nucleus.

DISEASE:
Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.

Similarity:
Belongs to the bZIP family.
Contains 1 bZIP domain.

Database links:

Entrez Gene: 7494 Human

Entrez Gene: 22433 Mouse

Entrez Gene: 289754 Rat

Omim: 194355 Human

SwissProt: P17861 Human

SwissProt: O35426 Mouse

SwissProt: Q9R1S4 Rat

Unigene: 437638 Human

Unigene: 469937 Mouse

Unigene: 101044 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Involvement in disease;Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7). Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
99久久综合国产精品免费 | 在线综合亚洲欧洲综合网站 | 亚洲自拍偷拍无码二区三区 | 九九热线有精品视频99 | 精品极品三大极久久久久 | 无码精品A∨在线观看中文 欧美激情视频在线观看一区二区三区 | 亚洲综合另类欧美久久久久精品 | 人妻少妇久久中文字幕app | 玩50岁四川熟女大白屁股直播 | 欧美精品免费一区二区三区 | 成年免费A级毛片免费看无码 | 精品国产污污免费网站入口 | 狠狠色噜噜狠狠狠狠色综合久 | 在线点播亚洲日韩国产欧美 | 国产麻豆一区二区三区精品视频 | 免费看成人AA片无码视频吃奶 | 在线中文字幕亚洲第一 | 伊人99综合精品视频 | 日日躁夜夜躁狠狠久久AV | 欧美a成人片在线观看 | a一级毛片视频免费看 | 97久久久人妻一区精品 | 亚洲一区二区三区乱码在线欧洲 | 日韩亚洲人成在线 | 国产精品亚洲av综合成久久久久久三级 | 暖暖、免费、高清、日本 | 国产精品一区二区三区四区五区 | 亚洲调教自慰喷水AV无码 | 中文字幕乱码免费视频 | 久久人人爽爽爽人久久久 | 国产欧美精品区一区二区三区 | 久久国产V一级毛多内射 | 国产精品内射久久久久欢欢 | 国产精品看高国产精品不卡 | 国产精品亚洲lv粉色 | 国产亚洲精品VA片在线播放 | 国产精品久久久久久亚洲内射 | 少妇高潮惨叫久久久久久电影 | 两个男用舌头到我的蕊花 | 亚洲AV成人无码网天堂 | 《久久国产91成人免费网站 |