亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
a级毛片免费全部播放无码,国产精品视频一区二区三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-XBP1/BF555 Conjugated antibody (bs-1668R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1668R-BF555
英文名稱 Rabbit Anti-XBP1/BF555 Conjugated antibody
中文名稱 BF555標記的細胞核轉(zhuǎn)錄因子X盒結(jié)合蛋白抗體
別    名 X box-binding protein-1; XBP-1; XBP1; XBP2; Tax responsive element binding protein 5; TREB5; X box binding protein 2; XBP 1; XBP2; XBP1_HUMAN; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; X-box-binding protein 1 in isoform 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Chicken, Cow, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29/40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human XBP-1 (51-90aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]

Function:
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.

Subcellular Location:
Nucleus.

DISEASE:
Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.

Similarity:
Belongs to the bZIP family.
Contains 1 bZIP domain.

Database links:

Entrez Gene: 7494 Human

Entrez Gene: 22433 Mouse

Entrez Gene: 289754 Rat

Omim: 194355 Human

SwissProt: P17861 Human

SwissProt: O35426 Mouse

SwissProt: Q9R1S4 Rat

Unigene: 437638 Human

Unigene: 469937 Mouse

Unigene: 101044 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Involvement in disease;Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7). Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩高清免费视频观看 | 人妻精品久久无码专区人妻 | 久久久精品天堂无码中文字幕 | 日本动态120秒免费 小宝极品内射国产在线 | 把女人弄爽大黄A大片片 | 欧美乱码精品一区二区三区卡 | 美女性爽视频国产免费 | 久久久久久九九99精品大 | 在线观看免费国产视频 | 亚洲AV日韩AV无码污污网站 | 绯色av入口一区二区三区 | 中文字幕一区二区在线观看 | 国产娱乐凹凸视觉盛宴在线视频 | 91久久国产最好的精华液 | 亚洲国产日韩欧美高清片a 黄色三级网站免费 | 免费一级做a爰片久久毛片潮喷 | 污视频在线免费观看网站 | 亚洲国产精品嫩草影院在线观看 | 婷婷色婷婷开心五月四房播播久久 | 精品国产乱码久久久久久浪潮 | 久久se精品一区精品二区 | 麻豆一区二区免费播放网站 | 又大又紧又粗c死你视频 | 国产真人无遮挡作爱免费视频 | 亚洲一区二区三区高清AV | 中文字幕 日韩 国产 | 亚洲日韩中文字幕A∨ | 国产乱人伦偷精品视频免下载 | 亚洲高清在线精品一区 | 2020精品极品国产色在线观看 | 久久久久88色偷偷免费成人 | 国产成人无码区免费内射一片色欲 | 国产成人精品免费视频大全 | 色妞色视频一区二区三区四区 | 亚洲AV产在线精品亚洲第一站 | 国产成人精品午夜福利在线播放 | 丝袜美腿国产综合久久 | 91资源在线播放 | 免费一级做a爰片久久毛片潮喷 | 性色AV性色生活片 | 99久久精品费精品国产一区二区 |