亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产成人精品综合在线观看,97se亚洲综合自在线尤物
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-EDIL3/Biotin Conjugated antibody (bs-7029R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7029R-Bio
英文名稱 Rabbit Anti-EDIL3/Biotin Conjugated antibody
中文名稱 生物素標記的表皮生長因子樣重復(fù)折疊1結(jié)構(gòu)域蛋白3抗體
別    名 DEL1; Developmental endothelial locus 1; Developmentally regulated endothelial cell locus 1 protein; EGF like repeat and discoidin I like domain containing protein 3; EGF like repeats and discoidin I like domains protein 3; Integrin binding protein DEL1; EDIL3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 心血管  細胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細胞粘附分子  內(nèi)皮細胞  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, ,Xenopuslaevis,Zebrafish)
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDIL3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EDIL3 is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3; also Del-1 and integrin-binding DEL1) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. Human EDIL3 is synthesized as a precursor with a 16 amino acid (aa) signal sequence and a 464 aa mature chain (SwissProt # O43854). The mature chain is composed of three epidermal growth factor (EGF) repeats and two discoidin-I-like domains. The second EGF repeat contains an RGD motif. Splicing variants produce two isoforms for human EDIL3. Isoform 2 has an A -> G substitution at aa 66 and a deletion of aa 67-76 found in isoform 1. Mature human EDIL3 shares 96% aa sequence identity with mature mouse EDIL3. The RGD motif of EDIL3 binds alpha v beta 5 integrin, which, in turn, leads to increased angiogenic transcription factor HoxD3 expression. HoxD3 activates alpha v beta 3 and uPA, resulting in the transformation of resting endothelial cells to an angiogenic state. EDIL3 becomes quiescent at the time of birth, and is no longer expressed in normal adult tissues. It has been found, however, re-expressed in a number of human tumors as well as in ischemic muscles and ischemic brain tissue, which may play an important role in adult angiogenesis. EDIL3 promotes adherence and migration of endothelial cells, and acts as an endothelial cell survival agent through upregulation of Bcl-2 expression. Exogenous application of EDIL3 has been demonstrated to augment angiogenesis and improve blood flow and tissue function in murine models of hind-limb ischemia, cardiac ischemia and cerebral ischemia. EDIL3 has also been shown to be an endogenous inhibitor of inflammatory cell recruitment by interfering with the integrin LFA-1-dependent leukocyte-endothelial adhesion.

Function:
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.

Subcellular Location:
Secreted.

Similarity:
Contains 3 EGF-like domains.
Contains 2 F5/8 type C domains.

Database links:

Entrez Gene: 10085 Human

Entrez Gene: 13612 Mouse

Entrez Gene: 688400 Rat

Omim: 606018 Human

SwissProt: O43854 Human

SwissProt: O35474 Mouse

Unigene: 482730 Human

Unigene: 125580 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲无码无线在线观看 | 国产超碰人人做人人爱ⅴA 一本久久a久久精品亚洲 | 午夜欧美精品久久久久久久 | 国产在线观看免费观看不卡 | 欧美人妻AⅤ中文字幕 | 国产偷窥盗摄一区二区 | 国产精品视频一区二区三区无码 | 国产精品无码无卡A级毛片 国产午夜精品理论片小yo奈 | 日本wwwxx爽69护士 | 亚洲人成色777777在线观看 | 小呦精品导航网站 | 白丝乳交内射一二三区 | 九色91精品国产网站 | 熟女少妇一区二区三区 | 白丝校花 扒腿自慰网站 | 一本大道香蕉久在线播放看 | 国产精品 久久久精品软件下载 | 粉嫩被两个粗黑疯狂进出 | 午夜精品一区二区三区在线观看 | 天天做天天爱天天爽综合网 | 久久久久久久久久久免费精品国产 | 99九九精品国产高清自在线 | 亚洲欧美综合国产精品一区看三级 | 99RE久久精品国产 | 动漫精品中文无码卡通动漫 | 亚洲欧美乱日韩乱国产 | 给我免费播放片高清在线观看 | 91精品国产成人网在线观看 | 亚洲日韩国产AV无码无码精品 | 18以下不能看的美女视频 | 综合在线视频精品专区 | 我们日本在线观看免费动漫下载 | 国产精品性做久久久久久 | 国产精品无码午夜福利免费看 | 中文字幕人妻熟女人妻A片 亚洲AV成人一区二区三区在线看 | 91久久精品日日躁夜夜躁欧美 | 国产一级无码免费不卡| 国产91在线高潮白浆在线观看 | 中文天堂网在线最新版 | 国产一级无码Av片在线观看 | 亚洲熟妇无码爱V在线观 |