亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
免费看男女下面日出水视频,纯肉高H肉辣浪荡NP论J,免费一级特黄欧美大片久久网
Rabbit Anti-CD171/L1CAM/Gold Conjugated antibody (bs-1996R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1996R-Gold
英文名稱 Rabbit Anti-CD171/L1CAM/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的神經(jīng)細(xì)胞粘附分子配體1抗體
別    名 Antigen identified by monoclonal; R1; CAML1; CD171; CD171 antigen; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1-NCAM; L1cam; L1CAM_HUMAN; MASA; MIC5; N CAML1; N-CAM-L1; NCAM-L1; NCAM-L1; NCAML1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; OTTHUMP00000025992; S10; SPG1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 發(fā)育生物學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長因子和激素  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 138kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD171
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq].

Function:
Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

DISEASE:
Defects in L1CAM are the cause of hydrocephalus due to stenosis of the aqueduct of Sylvius (HSAS) [MIM:307000]. Hydrocephalus is a condition in which abnormal accumulation of cerebrospinal fluid in the brain causes increased intracranial pressure inside the skull. This is usually due to blockage of cerebrospinal fluid outflow in the brain ventricles or in the subarachnoid space at the base of the brain. In children is typically characterized by enlargement of the head, prominence of the forehead, brain atrophy, mental deterioration, and convulsions. In adults the syndrome includes incontinence, imbalance, and dementia. HSAS is characterized by mental retardation and enlarged brain ventricles.
Defects in L1CAM are the cause of mental retardation-aphasia-shuffling gait-adducted thumbs syndrome (MASA) [MIM:303350]; also known as corpus callosum hypoplasia, psychomotor retardation, adducted thumbs, spastic paraparesis, and hydrocephalus or CRASH syndrome. MASA is an X-linked recessive syndrome with a highly variable clinical spectrum. Main clinical features include spasticity and hyperreflexia of lower limbs, shuffling gait, mental retardation, aphasia and adducted thumbs. The features of spasticity have been referred to as complicated spastic paraplegia type 1 (SPG1). Some patients manifest corpus callosum hypoplasia and hydrocephalus. Inter- and intrafamilial variability is very wide, such that patients with hydrocephalus, MASA, SPG1, and agenesis of corpus callosum can be present within the same family.
Defects in L1CAM are the cause of spastic paraplegia X-linked type 1 (SPG1) [MIM:303350]. Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.
Note=Defects in L1CAM may contribute to Hirschsprung disease by modifying the effects of Hirschsprung disease-associated genes to cause intestinal aganglionosis.
Defects in L1CAM are a cause of partial agenesis of the corpus callosum (ACCPX) [MIM:304100]. A syndrome characterized by partial corpus callosum agenesis, hypoplasia of inferior vermis and cerebellum, mental retardation, seizures and spasticity. Other features include microcephaly, unusual facies, and Hirschsprung disease in some patients.

Similarity:
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
Contains 5 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 3897 Human

Entrez Gene: 16728 Mouse

Entrez Gene: 50687 Rat

Omim: 308840 Human

SwissProt: P32004 Human

SwissProt: P11627 Mouse

SwissProt: Q05695 Rat

Unigene: 522818 Human

Unigene: 260568 Mouse

Unigene: 10378 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NCAM-L1又稱L1細(xì)胞粘附分子(L1CAM)是一種細(xì)胞表面糖蛋白,屬于免疫球蛋白超家族的神經(jīng)細(xì)胞粘附分子家族。L1CAM可能在神經(jīng)系統(tǒng)發(fā)育過程中發(fā)揮作用。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
A级毛片内射免费视频 | 狂躁美女BBBBBB视频 | 99re6这里只有精品视频在线观看 | 91TV国产人成在线播放免费 | 欧美精品九九99久久在免费线 | 日产无码久久久久久精品 | 老司机无码精品A | 亚州日本乱码一区二区三区 | 色综合99久久久无码国产精品 | 老师奶头好大我要摸视频 | 欧美日韩第一区二区三区 | 亚洲欧洲国产综合AV无码久久 | 肥老熟妇伦子伦456视频 | 精品国产在天天线在线 | 成人免费看AA片 | 老司机久久精品最新免费 | 无码成A毛片免费 | 内射白浆一区二区在线观看 | 国产精品一区在线麻豆 | 午夜男女爽爽爽免费播放 | 狠狠色老熟妇老熟女 | 精品久久久久久无码不卡 | 最近中文字幕在线看免费完整版 | 麻豆亚洲精品中文字幕一麻豆 | 国产精品久久久久无码AV | 久久精品国产免费观看频道 | 黄网站色视频大全免费观看 | 影音先锋女人av鲁色资源网久久 | 综合人妻久久一区二区精品 | 麻豆国产AV尤物网站尤物 | 精品视频在线观看视频免费视频 | 又黄又湿真实网站不付费 | 国产日韩欧美一区二区综合区 | 男女gif出入抽搐动态图 | 亚洲天堂免费在线 | 人妻美妇疯狂迎合系列视频 | 成全动漫视频在线观看完整版 | 精品在线观看一区 | 国产精品亚洲第一区在线 | 精品国产一区二区三区香蕉欧美 | 在线视频一区二区三区在线播放 |