亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美一级特黄乱妇高清视频 ,四虎永久在线精品国产免费,四川少妇BBB凸凸凸BBB
Rabbit Anti-KCNH1/PE-Cy3 Conjugated antibody (bs-2424R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2424R-PE-Cy3
英文名稱 Rabbit Anti-KCNH1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的鉀離子通道蛋白EAG1抗體
別    名 EAG1; EAG 1; EAG-1; KCNH 1; KCNH-1; h eag; Kv10.1; MGC124420; MGC142269; EAG; Ether a go go potassium channel 1; hEAG1; M eag; MGC124419; Potassium voltage gated channel subfamily H (eag related), member 1; Voltage gated potassium channel subunit Kv10.1; KCNH1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞周期蛋白  通道蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 111kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNH1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

Function:
Pore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts.

Subunit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH5/EAG2. Interacts with ALG10B (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells.

Similarity:
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.1/KCNH1 sub-subfamily.
Contains 1 cyclic nucleotide-binding domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain.

Database links:

Entrez Gene: 3756 Human

Entrez Gene: 16510 Mouse

Entrez Gene: 65198 Rat

Omim: 603305 Human

SwissProt: O95259 Human

SwissProt: Q60603 Mouse

SwissProt: Q63472 Rat

Unigene: 553187 Human

Unigene: 4489 Mouse

Unigene: 11071 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

KCNH1鉀通道蛋白在調(diào)控細(xì)胞增殖和細(xì)胞周期進(jìn)程中起重要作用。Eag1是膜蛋白, 參與細(xì)胞信號(hào)轉(zhuǎn)導(dǎo), 在正常組織和惡性腫瘤中有獨(dú)特的表達(dá)特點(diǎn).
一些離子通道如鉀、鈣、氯、鈉等通道與腫瘤相關(guān),特別是鉀通道與腫瘤的關(guān)系最為密切。鉀通道是細(xì)胞膜上種類最多、最為復(fù)雜的一類離子通道,它存在于多種細(xì)胞中,是細(xì)胞膜電位的重要控制因素。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
中文字幕一区二区日韩欧美 | 亚洲国产成人精品刺激内射白浆 | 免费大片av手机看片 | 97人人模人人爽人人 | 动漫爆乳无遮挡免费观看 | 日韩成人精品视频免费专区 | 一级毛片免费不卡在线 | 色欲狠狠躁天天躁无码中文字幕 | 免费精品国产自产拍在线观看图片 | 91精品国产日韩91久久久久久 | 两根撑到极致哭着求饶h | 96精产国品一二三产品区别 | 亚洲激情无码一区二区三区 | 超级最爽的乱淫片免费 | 欧美激情一区二区三区视频 | 久久久久久一级毛片免费野外 | 国产末成年女噜噜片 | 日本真实娇小XXXX | 最新亚洲中文字幕一区在线 | 麻花传媒永久免费版的特色 | 精品亚洲A∨无码一区二区三区 | 午夜精品成人一区二区视频 | 一本一道精品欧美中文字幕 | 国模丽丽啪啪一区二区 | 天堂网在线最新版www资源网 | 国产精品人人爽人人做我的可爱 | 欧美日韩在线精品一区二区三区激情综合 | 国产偷窥盗摄一区二区 | 很黄很黄地在床视频女 | 成年美女黄网站色大免费全看 | 动漫AV网站免费观看 | 真人插B免费视频播放 | 内射后入蘑菇视频ONLYYOU | 男女高潮嘿咻激烈爱爱动态图 | 国产高清乱码又大又圆 | 午夜国产精品秘 入口竹菊 一区二区日本视频 | 国产欧美日韩一区二区搜索 | 色欲狠狠躁天天躁无码中文字幕 | 久久久久亚洲AV成人人电影 | 2019午夜福利不卡片在线 | 中文字幕久久久久久久免费 |