亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产寡妇婬乱A毛片视频,水野优香vagu224在线播放
Rabbit Anti-ZIC3/PE Conjugated antibody (bs-11608R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11608R-PE
英文名稱 Rabbit Anti-ZIC3/PE Conjugated antibody
中文名稱 PE標(biāo)記的內(nèi)臟異位相關(guān)蛋白/鋅指蛋白203抗體
別    名 Heterotaxy 1; HTX; HTX1; ZIC 3; Zic family member 3 (odd paired Drosophila homolog heterotaxy 1); Zic family member 3; Zic3; ZIC3_HUMAN; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3); Zinc finger protein ZIC 3; ZNF203.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC3 (331-410aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zic3 is a C2H2 zinc finger transcription factor that establishes a proper left-right axis and midline neural patterning during early development of the vertebrate embryo. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. Zic3 mutations in the zinc finger DNA binding domain and in the N-terminal domain result in loss of reporter gene transactivation, and mutations between amino acids 253-323 of the Zic3 protein causes aberrant cytoplasmic localization rather than the wild type nuclear localization.

Function:
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

Subcellular Location:
Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.

DISEASE:
Defects in ZIC3 are the cause of visceral heterotaxy X-linked type 1 (HTX1) [MIM:306955]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy X-linked type 1 include dextrocardia, corrected transposition of great arteries, ventricular septal defect, patent ductus arteriosus, pulmonic stenosis, situs inversus viscerum, and asplenia and/or polysplenia.
Defects in ZIC3 are a cause of VACTERL association X-linked with or without hydrocephalus (VACTERLX) [MIM:314390]. A syndrome characterized by vertebral anomalies, anal atresia, cardiac malformations, tracheoesophageal fistula, renal anomalies (urethral atresia with hydronephrosis), and limb anomalies (hexadactyly, humeral hypoplasia, radial aplasia, and proximally placed thumb). Some patients may have hydrocephalus. Some cases of VACTERL-H are associated with increased chromosome breakage and rearrangement.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7547 Human

Entrez Gene: 22773 Mouse

Entrez Gene: 367944 Rat

Omim: 300265 Human

SwissProt: O60481 Human

SwissProt: Q62521 Mouse

Unigene: 111227 Human

Unigene: 255890 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产高清av首播原创麻豆 | 国产真实乱子伦精品视频 | 日本高清专区一区二无线 | 狠狠的撞进去嗯啊h女强男视频 | 国产成人精品久久久亚洲综合一区色婷婷 | 欧美精品69videosex性欧美 | 亚洲无线码在线一区观看 | 久青青视频精品免费观看 | 成 人片 黄 色 大 片 | 麻豆AV无码精品一区二区 | 91精品国产色综合久久不卡美美 | 又大又粗欧美黑人AAAAA片 | 亚洲第一区第二区 | 无码不卡中文字幕一区二区三区 | 国产精品福利在线播放 | 91麻豆国产精品91久久久 | 亚洲成人电影在线观看精品国产 | 午夜精品久久久久久久99热 | 久久中文字幕亚洲一区二区 | 久久人人爽人人爽人人片AV不 | 日韩无码高清福利在线看 | 99爱在线精品视频网站 | 国产性夜夜春夜夜爽1A片 | 污全彩肉肉无遮挡彩色 | 欧美日韩精品国产一区在线 | 狠狠色丁香婷婷久久综合 | 国产精品亚欧美一区二区 | 中文字幕久久久久久一区二区三区 | 日韩毛片AV无码免费一区二区三区 | 久久国产亚洲电影天堂 | 毛片成人永久免费视频 | 精品乱码一区二区三区四区 | 国偷自产AV一区二区三区健身房 | 中文字幕无码家庭乱欲 | 国产麻豆天美果冻无码视频 | 囯产精品一区二区三区线 | 亚洲AV午夜福利无码精品一区 | 亚洲最大视频网站 | 久久国产精品-久久精品 | 性色爽爱性色爽爱网站 | heyzo1754北岛玲在线视频 |