亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
国产一区二区无码蜜芽精品,亚洲日韩国产AV无码无码精品,一级做a爱全免费视频99
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ZIC3/BF350 Conjugated antibody (bs-11608R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11608R-BF350
英文名稱 Rabbit Anti-ZIC3/BF350 Conjugated antibody
中文名稱 BF350標記的內臟異位相關蛋白/鋅指蛋白203抗體
別    名 Heterotaxy 1; HTX; HTX1; ZIC 3; Zic family member 3 (odd paired Drosophila homolog heterotaxy 1); Zic family member 3; Zic3; ZIC3_HUMAN; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3); Zinc finger protein ZIC 3; ZNF203.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發(fā)育生物學  干細胞  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC3 (331-410aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zic3 is a C2H2 zinc finger transcription factor that establishes a proper left-right axis and midline neural patterning during early development of the vertebrate embryo. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. Zic3 mutations in the zinc finger DNA binding domain and in the N-terminal domain result in loss of reporter gene transactivation, and mutations between amino acids 253-323 of the Zic3 protein causes aberrant cytoplasmic localization rather than the wild type nuclear localization.

Function:
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

Subcellular Location:
Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.

DISEASE:
Defects in ZIC3 are the cause of visceral heterotaxy X-linked type 1 (HTX1) [MIM:306955]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy X-linked type 1 include dextrocardia, corrected transposition of great arteries, ventricular septal defect, patent ductus arteriosus, pulmonic stenosis, situs inversus viscerum, and asplenia and/or polysplenia.
Defects in ZIC3 are a cause of VACTERL association X-linked with or without hydrocephalus (VACTERLX) [MIM:314390]. A syndrome characterized by vertebral anomalies, anal atresia, cardiac malformations, tracheoesophageal fistula, renal anomalies (urethral atresia with hydronephrosis), and limb anomalies (hexadactyly, humeral hypoplasia, radial aplasia, and proximally placed thumb). Some patients may have hydrocephalus. Some cases of VACTERL-H are associated with increased chromosome breakage and rearrangement.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7547 Human

Entrez Gene: 22773 Mouse

Entrez Gene: 367944 Rat

Omim: 300265 Human

SwissProt: O60481 Human

SwissProt: Q62521 Mouse

Unigene: 111227 Human

Unigene: 255890 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.a6308.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
国产精品毛片久久久久久久 | 中文字日产幕码三区的做法大全 | 中文字幕日产乱码久久久 | 久久这里只有精品1 | 可以在线看av的网站 | 日韩一区二区三免费高清 | a级毛片无码免费真人久久 国产精品视频一区二区三区不卡 | 极品少妇被后入内射视 | 爽到高潮无码视频在线观看 | 一级欧美一级日韩片老司机99 | 高清一级毛片一本到免费观看 | 成人MV射精无打码视频 | 国产伦精品免编号公布 | 无码国产精品午夜福利v | 大学生一级毛片全黄真人无码 | H女主从小被C到大荤话小说 | 内射夜晚在线观看 | 国产精品久久久久久亚洲小说 | 性色AV一区二区三区咪爱四虎 | 国产精品亚洲av综合成久久久久久三级 | 中文字幕不卡一区二区三区 | 青春禁区在线观看免费 | 精品亚洲AV无码喷奶水在线观看 | 粉嫩大学生无套内射无码专区久久 | 国产欧美一区二区精品仙草咪 | 久久久精品国产亚洲AV综合 | 91精品国产91热久久p | 丁香五月亚洲综合深深爱 | 最近的2019中文字幕无吗 | 国产精品无码免费专区午夜 | 欧美亚洲精品中文字幕乱码免费高清 | 一本久久a久久精品免费不卡 | 成人网站免费大全日韩国产 | 使劲快高潮了国语对白在线 | 亚洲综合色婷婷七月丁香 | 搡BBBB搡BBBB搡BBBB | 中文字幕AV在线一二三区 | 久久这里只有精品视频6 | 4455vw亚洲毛片 | 中文无码精品一区二区三区 | 亚洲精品国产不卡在线观看 |