亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品久久久精品无码,蜜桃精品免费久久久久影院
Rabbit Anti-ZIC3/BF594 Conjugated antibody (bs-11608R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11608R-BF594
英文名稱 Rabbit Anti-ZIC3/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的內(nèi)臟異位相關(guān)蛋白/鋅指蛋白203抗體
別    名 Heterotaxy 1; HTX; HTX1; ZIC 3; Zic family member 3 (odd paired Drosophila homolog heterotaxy 1); Zic family member 3; Zic3; ZIC3_HUMAN; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3); Zinc finger protein ZIC 3; ZNF203.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC3 (331-410aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zic3 is a C2H2 zinc finger transcription factor that establishes a proper left-right axis and midline neural patterning during early development of the vertebrate embryo. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. Zic3 mutations in the zinc finger DNA binding domain and in the N-terminal domain result in loss of reporter gene transactivation, and mutations between amino acids 253-323 of the Zic3 protein causes aberrant cytoplasmic localization rather than the wild type nuclear localization.

Function:
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

Subcellular Location:
Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.

DISEASE:
Defects in ZIC3 are the cause of visceral heterotaxy X-linked type 1 (HTX1) [MIM:306955]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy X-linked type 1 include dextrocardia, corrected transposition of great arteries, ventricular septal defect, patent ductus arteriosus, pulmonic stenosis, situs inversus viscerum, and asplenia and/or polysplenia.
Defects in ZIC3 are a cause of VACTERL association X-linked with or without hydrocephalus (VACTERLX) [MIM:314390]. A syndrome characterized by vertebral anomalies, anal atresia, cardiac malformations, tracheoesophageal fistula, renal anomalies (urethral atresia with hydronephrosis), and limb anomalies (hexadactyly, humeral hypoplasia, radial aplasia, and proximally placed thumb). Some patients may have hydrocephalus. Some cases of VACTERL-H are associated with increased chromosome breakage and rearrangement.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7547 Human

Entrez Gene: 22773 Mouse

Entrez Gene: 367944 Rat

Omim: 300265 Human

SwissProt: O60481 Human

SwissProt: Q62521 Mouse

Unigene: 111227 Human

Unigene: 255890 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
午夜熟女插插XX免费视频 | 国产精品久久久久三级无码 | 国产又爽又黄无码无遮挡在线观点 | 亚洲AV无码一二区三区在线播放 | 三级日本高清完整版热播 | 国产精品伦一区二区三级视频 | 蜜桃精品免费久久久久影院 | 在线观看免费av网站 | 日产亚洲一区二区三区 | а√在线中文网新版地址在线 | 亚洲午夜精品无码专区在线播放 | 精品人妻中文字幕乱码 | ww男人的天堂视频在线观看 | 亚洲乱码日产精品BD在线看 | 4455vw亚洲毛片 | 精品国产乱码久久久EA7 | 久99视频精品免费观看福利 | 久久国产一区二区三区 | 国产成人Av大片在线观看 | 免费看成人AA片无码视频吃奶 | 我把护士日出水了视频90分钟 | 国产香蕉九九久久精品免费 | 婷婷国产精品久久久久精 | 国产亚洲综合99久久系列 | 国产精品久久久久9999小说 | 扒开老师大腿猛进AAA片软件 | 男人的好看免费观看在线视频 | 久久久久亚洲AV成人人人 | 日本熟妇丰满XXXXX18 | 特黄三级又爽又粗又大 | 免费国产黄网站在线观看可以下载 | 久久99蜜桃精品久久久久小说 | BL肉YIN荡受NP各种PL同性 | 一区二区视频在线观看高清视频在线 | 少妇被粗大猛烈进出免费视频 | 成人H动漫精品一区二区 | 看**视频一一级毛片 | 永久黄网站色视频免费观看 | 亚洲一区二区三区高清网 | 狂躁美女大BBBBBB视频1 | 久久久久亚洲AV成人片乱码 |