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Rabbit Anti-BAFF/APC Conjugated antibody (bs-2431R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2431R-APC
英文名稱 Rabbit Anti-BAFF/APC Conjugated antibody
中文名稱 APC標記的TNF家族B細胞激活因子抗體
別    名 ApoL related ligand TALL 1; B cell Activating Factor; B lymphocyte stimulator ; BLYS; CD 257; CD257; CD257 antigen; delta BAFF; Dendritic cell derived TNF like molecule; DTL; DTL precursor; TALL 1; TALL1; THANK; TNF and APOL related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNF homolog that activates apoptosis NKFB and JNK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 20; Tumor necrosis factor like protein ZTNF4; Tumor necrosis factor superfamily member 13B; ZTNF4; TN13B_MOUSE .  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  生長因子和激素  激酶和磷酸酶  細胞分化  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Rabbit, )
產(chǎn)品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse BAFF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq].

Function:
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.

Subunit:
Belongs to the tumor necrosis factor family.

Subcellular Location:
Secreted and Cell membrane.

Tissue Specificity:
Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.
Isoform 2 is not efficiently shed from the membrane unlike isoform 1.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 10673 Human

Entrez Gene: 24099 Mouse

Omim: 603969 Human

SwissProt: Q9Y275 Human

SwissProt: Q9WU72 Mouse

Unigene: 525157 Human

Unigene: 596110 Human

Unigene: 28835 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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