亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
92婷婷伊人久久精品一区,永久中文字幕免费视频网站,国产精品内射久久久久欢欢
Rabbit Anti-UCHL3/BF594 Conjugated antibody (bs-11676R-BF594)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11676R-BF594
英文名稱 Rabbit Anti-UCHL3/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的泛素硫酯酶L3抗體
別    名 Ubiquitin carboxyl-terminal hydrolase isozyme L3; Ubiquitin thioesterase L3; Ubiquitin thiolesterase; Ubiquitin thiolesterase L3; UCH L3; UCH-L3; UCHL3; UCHL3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  泛素  Alzheimer's  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UCHL3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

Function:
Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3". Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory.

Subunit:
Preferentially binds diubiquitin; the interaction does not hydrolyze diubiquitin but, in vitro, inhibits the hydrolyzing activity on other substrates.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Highly expressed in heart, skeletal muscle, and testis.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the peptidase C12 family.

Database links:

Entrez Gene: 7347 Human

Entrez Gene: 50933 Mouse

Entrez Gene: 498560 Rat

Omim: 603090 Human

SwissProt: P15374 Human

SwissProt: Q9JKB1 Mouse

SwissProt: Q91Y78 Rat

Unigene: 162241 Human

Unigene: 275970 Mouse

Unigene: 145487 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产欧美日韩一区二区三区 | 好大好硬好爽好深好硬视频 | 日本免费在线观看视频 | 亚洲成人电影在线观看精品国产 | 91看片淫黄大片在看 | 亚洲中文字幕在线一区播放 | 久久无码精品一区二区三区 | 亚洲国产成人久久一区WWW | 成全视频高清免费观看在线动漫 | 野花视频在线观看高清免费完整版 | 久久国产精品99久久久久久老狼 | 青青国产成人久久111网站 | 白丝初音未来被调教出奶水 | 久久久久久久久久国产精品免费 | 亚洲欧美日韩在线观看一区二区三区 | 很很鲁很很在线视频97 | 久久国产精品偷任你爽任你A | 97人人爽人人爽爽人人一区二区 | 另类重口bdsm日本tv | 老司机久久精品最新免费 | 丁香五月亚洲综合深深爱 | 亚洲精品国产高清不卡在线 | 亚洲精品无码久久毛片 | 13小箩利无码视频网站免费 | 久色乳综合思思在线视频 | 一级A爱做片免费观看国产 成人MV射精无打码视频 | 内射国产老熟女综合导航 | 精品国语对白清晰在线 | 一级特黄大片欧美久久久久久 | 一级特黄性色生活片一区二区 | 91精品久久久久久久久久小网站 | 成年性生交大片免费看 | 97se色在在线视频 | 51吃瓜中心-吃最新最真的瓜 | 午夜AV内射一区二区三区红桃视 | 强奸伦久久久久久久久久久特级av | 欧美日韩视频一视频二视频三 | 无码免费婬AV片在线观看 | 9九色桋品熟女内射 | 精品人妻中文字幕在线 | 亚洲AV无码李区亚洲A |