亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产欧美日韩精品一区二区三区蜜桃不卡,久久黄色免费网站
Rabbit Anti-PROSAAS/Cy3 Conjugated antibody (bs-11686R-Cy3)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-11686R-Cy3
英文名稱(chēng) Rabbit Anti-PROSAAS/Cy3 Conjugated antibody
中文名稱(chēng) Cy3標(biāo)記的枯草溶菌素轉(zhuǎn)化酶1抑制劑抗體
別    名 b-LEN; b-PEN-LEN; b-SAAS; Big LEN; granin like neuroendocrine peptide; l-LEN; l-SAAS; N-proSAAS; PCSK1_HUMAN; Pcsk1n; pro-SAAS; Proprotein convertase 1 inhibitor; Proprotein convertase subtilisin/kexin type 1 inhibitor; PROSAAS; SAAS; SAAS CT(1-49); SAAS CT(25-40).  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  泛素  Alzheimer's  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PROSAAS (34-130aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

Function:
May function in the control of the neuroendocrine secretory pathway. Proposed be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the further processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 84 kDa form but not the autocatalytically derived 66 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. May control the intracellular timing of PCSK1 rather than its total level of activity. The function of the processed secreted peptides is not known.

Subunit:
Interacts via the C-terminal inhibitory domain with PCSK1 66 kDa form

Subcellular Location:
Secreted. Golgi apparatus > trans-Golgi network. A N-terminal processed peptide, probably Big SAAS or Little SAAS, is accumulated in cytoplasmic protein tau deposits in frontotemporal dementia and parkinsonism linked to chromosome 17 (Pick disease), Alzheimer disease and amyotrophic lateral sclerosis-parkinsonism/dementia complex 1.

Tissue Specificity:
Expressed in brain and pancreas.

Post-translational modifications:
Proteolytically cleaved in the Golgi.
O-glycosylated with a core 1 or possibly core 8 glycan.

Database links:

Entrez Gene: 27344 Human

Omim: 300399 Human

SwissProt: Q9UHG2 Human

Unigene: 522640 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产性自爱拍偷在在线播放 | 国产内射爽爽大片视频社区在线 | 日韩人妻少妇一区二区三区 | 久久久久久九九99精品大 | 国产欧美日韩一区二区搜索 | 国产日产欧产精品精品 | 久久国产精品国产精品 | 亚洲欧美乱日韩乱国产 | 日韩欧美视频一区 | 国产午夜影视大全免费观看 | 女人高潮久久久叫人喷水 | 亚洲中文乱码AV网站 | 全部在线播放免费毛片 | 亚洲无码一区二区三区 | 国产一级a毛一级a做免费图片 | 囯精产品一品二品国精91 | 在线综合亚洲欧洲综合网站 | 99精品亚洲国产精品久久不卡 | 蜜桃日本免费看MV免费版 | 欧美a成人片在线观看 | 日韩十八禁在线1区2区3区不卡 | 久久久久久一级毛片免费野外 | XXXX18一20岁HD第一次 | 国产欧美精品亚洲日本一区 | 美女内射毛片在线看3D | 日本按摩高潮s级中文片 | 欧美日韩激情无码专区 | 中文字幕熟妇久久久人妻 | 色狠台湾色综合网站 | 日日操夜夜操视频 | 国产女人18毛片水真多1 | 国产一区二区三区在线看片 | 欧美日韩成人VA精品一区二区三区不卡 | 亚洲AV无码一二区三区在线播放 | 一级毛片丰满**出奶水 | 亚洲国产成人精品刺激内射白浆 | 欧美精品视频一区二区三区不卡 | 91麻豆精品一二三区在线 | 青青草原免费在线视频 | 国产v综合v亚洲欧美大片 | 亚洲日韩精品国产3区 |