亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产综合色香蕉精品五夜婷 ,国产成人精品自在钱拍,无码国产亚洲日韩国精品视频一区二区三区
Rabbit Anti-HECW1/Cy5 Conjugated antibody (bs-11692R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11692R-Cy5
英文名稱 Rabbit Anti-HECW1/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的肌萎縮側(cè)索硬化癥相關(guān)蛋白HECW1抗體
別    名 NEDL1; C2 and WW domain-containing protein 1; E3 ubiquitin-protein ligase HECW1; HECT; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECW 1; Hecw1; HECW1_HUMAN; hNEDL1; NEDD4 like ubiquitin protein ligase 1; NEDD4-like E3 ubiquitin-protein ligase 1; NEDL-1; NEDL 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 179kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HECW1 (251-350aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
NEDL1 is a 1,606 amino acid cytoplasmic protein predominantly expressed in neurons of adult and fetal brain. NEDL1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. NEDL1 mediates ubiquitination and subsequent degradation of Dvl-1 and targets mutant SOD-1. NEDL1 forms cytotoxic aggregates with Dvl, TRAP-?and mutant SOD1 that lead to motor neuron death in FALS (familial amyotrophic lateral sclerosis). individuals affect by FALS (also known as Lou Gehrig's disease) experience muscle weakness and atrophy throughout the body. FALS is caused by the degeneration of upper and lower motor neurons resulting in loss of signal to muscles.

Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Subunit:
Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.

Similarity:
Contains 1 C2 domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 2 WW domains.

Database links:

Entrez Gene: 23072 Human

Omim: 610384 Human

SwissProt: Q76N89 Human

Unigene: 164453 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
免费一级特黄欧美大片久久网 | 国产AAA片精品网站 打扑克污黄对网站在线看 男女激情射精国产精品久久 | 国产-第1页-浮力影院 | 又爽又高潮的BB视频免费看 | 中文字幕一区视频一线 | 人妻少妇看A偷人无码精品 荡公乱妇蒂芙尼中文字幕 爆乳JK美女脱内衣裸体网站 | 日韩久久精品无码一二级 | 日韩亚洲人成网站在线播放 | 欧美激情一区二区三区蜜桃视频 | 无码AV熟妇素人内射V在线 | 国产在线视频福利 | 日本一二三不卡视频 | 91精品国产91久久久久久青草 | 久久久SS麻豆欧美国产日韩 | 99国产亚洲精品无码成人69V | 日本工口里番H彩色无遮挡全彩 | 精品乱子伦一区二区三区 | 国产乱子伦精品无码码专区 | 中文熟妇人妻又伦精品 | 10000部拍拍拍免费视频 | 香蕉国产片一级一级一级一级 | 国产精品动漫网站入口大全 | 国产GAYSEXCHINA男外卖 | 免费在线观看一区 | 99久久综合国产精品免费 | 精品国产乱码久久久久久呢 | 24小时在线观看视频免费 | 91人人人玩人人妻精品99 | 91久久精品日日躁夜夜躁欧美 | 日韩欧美国产偷亚洲清高 | 在线观看不卡无码国产 | 丰满少妇女人A毛片视频 | 国产午夜精品片一区二区三区 | 久久综合久久自在自线精品自 | 国产精品性做久久久久久 | 少妇人妻上班偷人精品免费 | AV无码免费一区二区三区不卡 | 内射人妻精品丨色AV无码 | AV无码久久久久不卡网站毛片 | 黑人啊灬啊灬啊灬快灬深用口述 | 18禁美女裸体网站免费扒内衣 |