亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品91在线播放久,亚洲国产美女视频,国产欧美日韩综合精品一区二区
Rabbit Anti-HECW1/APC Conjugated antibody (bs-11692R-APC)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-11692R-APC
英文名稱(chēng) Rabbit Anti-HECW1/APC Conjugated antibody
中文名稱(chēng) APC標(biāo)記的肌萎縮側(cè)索硬化癥相關(guān)蛋白HECW1抗體
別    名 NEDL1; C2 and WW domain-containing protein 1; E3 ubiquitin-protein ligase HECW1; HECT; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECW 1; Hecw1; HECW1_HUMAN; hNEDL1; NEDD4 like ubiquitin protein ligase 1; NEDD4-like E3 ubiquitin-protein ligase 1; NEDL-1; NEDL 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 179kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HECW1 (251-350aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
NEDL1 is a 1,606 amino acid cytoplasmic protein predominantly expressed in neurons of adult and fetal brain. NEDL1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. NEDL1 mediates ubiquitination and subsequent degradation of Dvl-1 and targets mutant SOD-1. NEDL1 forms cytotoxic aggregates with Dvl, TRAP-?and mutant SOD1 that lead to motor neuron death in FALS (familial amyotrophic lateral sclerosis). individuals affect by FALS (also known as Lou Gehrig's disease) experience muscle weakness and atrophy throughout the body. FALS is caused by the degeneration of upper and lower motor neurons resulting in loss of signal to muscles.

Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Subunit:
Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.

Similarity:
Contains 1 C2 domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 2 WW domains.

Database links:

Entrez Gene: 23072 Human

Omim: 610384 Human

SwissProt: Q76N89 Human

Unigene: 164453 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
毛片线看免费观看 | 久久综合九色综合欧美就去吻 | 超级乱淫小黄文小说 | 国产精品免费一区二区三区四区 | 性色A码一区二区三区天美传媒 | 久久99蜜桃精品久久久久 | 亚洲精品白浆高清久久久久久 | 暖暖、免费、高清、日本 | 色综合伊人色综合网站 | 黄色视频在线观看网站 | 欧美片内射欧美美美妇 | 美女内射视频WWW网站午夜 | 日本精品久久久久中文字幕 | 91精品国产麻豆国产自产在线 | 成全动漫视频在线观看完整版 | 中文国产高清综合乱色视频在线播放 | 中文字幕无码人妻AAA片 | 人妻久久相姦中文字幕 | 伊人天伊人天天综合网 | 国产无遮挡无码视频在线观看不卡 | 黄色视频网站在线免费观看 | 日韩十八禁在线1区2区3区不卡 | 91麻豆国产精品91久久久 | 最近中文字幕在线看免费完整版 | 国产欧美综合在线观看第十页 | 日韩高清一区二区三区不卡 | 一本一本久久a久久精品66 | 永久免费A片在线观看无码 免费一级A片毛毛片在线播放99 | 国产午夜三级一区二区三 | 午夜在线观看视频免费成人 | 国产福利一区二区三区在线观看 | 夜里十大禁用短视频软件 | 人妻无码专区一专区二专区三 | 成 人 黄 色 免费 网站无毒 | 四虎永久在线精品国产免费 | 91精品久久久久久中文字幕 | 美女祼体无遮挡又污又黄又爽视频在线看 | 国产精品国产三级国产an | 美妇乱人伦视频中文字幕 | 在线精品亚洲欧美日韩国产 | 又黄又湿免费高清视频 |