亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
性欧美18处19处破在线观看,亚洲AV无码乱码在线观看性色,成人做受120秒试看动态图
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-Mcl1 (Ser159 + Thr163)/PE-Cy7 Conjugated antibody (bs-3265R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3265R-PE-Cy7
英文名稱 Rabbit Anti-Phospho-Mcl1 (Ser159 + Thr163)/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的磷酸化髓樣細胞白血病-1抗體
別    名 Mcl1 (phospho S159/T163); Mcl1 (phospho Ser159/Thr163); p-Mcl1 (Ser159/Thr163); myeloid cell leukemia 1; myeloid cell leukemia sequence 1; MCL-1; MCL1L; MCL 1; mcl1/EAT; MGC104264; MGC1839; TM; MCL1S; EAT) Bcl 2 related protein EAT/mcl1; BCL2 related; BCL2L3; EAT; Induced myeloid leukemia cell differentiation protein Mcl 1; myeloid cell leukemia sequence 1; Myeloid cell leukemia sequence 1 BCL2 related; Myeloid cell leukemia sequence 1 isoform 1; OTTHUMP00000032794; OTTHUMP00000032795; TM; MCL1; bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.

Function:
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Subunit:
Interacts with BAD, BOK, BIK and BFM (By similarity). Interacts with PMAIP1. Isoform 1 interacts with BAX, BAK1, TPT1 and BCL2L11. Heterodimer of isoform 1 and isoform 2. Homodimers of isoform 1 or isoform 2 are not detected. Isoform 2 does not interact with pro-apoptotic BCL2-related proteins.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential). Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria.

Post-translational modifications:
Cleaved by CASP3 during apoptosis. In intact cells cleavage occurs preferentially after Asp-127, yielding a pro-apoptotic 28 kDa C-terminal fragment.
Rapidly degraded in the absence of phosphorylation on Thr-163 in the PEST region.
Phosphorylated on Thr-163. Treatment with taxol or okadaic acid induces phosphorylation on additional sites.

Similarity:
Belongs to the Bcl-2 family.

Database links:

Entrez Gene: 4170 Human

Entrez Gene: 17210 Mouse

Entrez Gene: 60430 Rat

Omim: 159552 Human

SwissProt: Q07820 Human

SwissProt: P97287 Mouse

SwissProt: Q9Z1P3 Rat

Unigene: 632486 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Mcl1蛋白是bcl-2家族成員,它在調(diào)控腫瘤細胞的凋亡、增殖、分化等過程中起一定作用。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
91成人啪国产啪永久地址 | 国产精品毛片VA一区二区三区 | 东京热男人aV天堂 | 成人毛片100免费观看 | 日韩欧美一区二区三区在线视频 | 日本黄H兄妹H动漫一区二区三区 | 丰满少妇被猛烈进入毛片 | 人妻熟妇久久久久久精品无码 | 亚洲一区二区三区女厕偷拍 | 国产成A人亚洲精V品无码樱花 | 被CAO哭高H野外NP小说男男 | 人妻内射一区二区在线视频 | 无码AV大香线蕉伊人久久九色 | 亚洲国产成人在线视频 | 国产精品无码久久久最线观看 | 国产欧美日韩一区二区搜索 | 精品亚洲A∨无码一区二区三区 | 一本大道中文日本香蕉 | 亚洲精品无码久久久久久久久 | 精品粉嫩国产48尤物在线播放 | 白丝校花扒腿让我c在线观看 | 永久免费观看的黄网站 | 青春草无码精品视频在线观看 | 国产在线观看片免费人成视频 | 国产免费无码XXXXX视频 | 少妇高潮灌满白浆毛片免费看 | 久久久这里只有精品加勒比 | 91久久精品美女高潮喷水白浆 | 国产精品原创巨作AV | 91精品免费久久久久久久久 | 国产一级毛片国产 | 欧美gαy男男激情1069 | 91九色视频在线观看 | 狠狠色丁香久久婷婷综合_中 | 情趣白丝女仆下部被揉小说合集 | AV午夜午夜快憣免费观看 | 国产激情久久久久99蜜桃小说 | 中国黄色毛片大片 | 最近2019年中文字幕无吗 | 无码人妻精品一区二区蜜桃色 | 国模白灵私拍[150P] |