亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
荡公乱妇蒂芙尼中文字幕,国产日韩中文字幕,青春草视频在线观看
Rabbit Anti-Deltex 1/RBITC Conjugated antibody (bs-0399R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0399R-RBITC
英文名稱 Rabbit Anti-Deltex 1/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的DTX1抗體
別    名 Deltex protein 1; Deltex; Deltex-1; Deltex1; Dtx1; FXI-T1; Fxit 1; Fxit1; mDTX1; DTX1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Deltex-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Deltex is a RING finger ubiquitin ligase which is conserved from Drosophila to Humans and is a regulator of Notch signaling pathway. Deltex regulates both B-cell lineage and splenic marginal-zone B-cell commitment. Deltex is implicated in neurogenesis, lymphogenesis and myogenesis as well as marginal zone B cell differentiation.

Function:
Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

Subunit:
Homodimer. May form a heterodimer with other members of the Deltex family. Interacts with NOTCH1 via its N-terminus region and EIF3F, the interaction is required for NOTCH1 deubiquitination. Interacts with EP300. Forms a heterodimer with BBAP; the heterodimerization leading to an increase of in vitro ubiquitin ligase activity. Interacts with ITCH.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associates with endocytic vesicles. Partially nuclear.

Tissue Specificity:
Widely expressed. Strongly expressed in blood vessel. Also expressed in embryonic nervous system, pancreas, lung, adrenal gland, digestive tube and muscles. Expressed in MZB cells and developing B- and T-cells.

Post-translational modifications:
Ubiquitinated; undergoes 'Lys-29'-linked polyubiquitination catalyzed by ITCH.

Similarity:
Belongs to the Deltex family.
Contains 1 RING-type zinc finger.
Contains 2 WWE domains.

Database links:

Entrez Gene: 1840 Human

Entrez Gene: 14357 Mouse

Omim: 602582 Human

SwissProt: Q86Y01 Human

SwissProt: Q61010 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Deltex1用于老年滯呆、神經(jīng)退行性變的研究。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
色欲久久久久久综合网精品 | 国产又黄又爽胸又大免费视频 | 天天躁日日躁狠狠躁AV麻豆 | 久久99精品久久久久久清纯直播 | 熟妇丰满videosxxxxx | 色久综合网精品一区二区 | 女人被狂躁到爽动态gif图 | 国产性夜夜春夜夜爽1A片 | 黄色毛片在线观看 | 国产精品一区二区久久宅男宅女 | 国产欧美一区二区三区免费 | 国产精品老熟女视频一区二区 | 国产精品久久一区二区三区蜜桃 | 亚洲乱妇老熟女爽到高潮的片 | 无码精品人妻一区二区三区涩爱 | 国产精品久久久久久久福利竹菊 | 热99re久久精品国产首页免 | 亚洲精品高清一二区久久 | 男男体育生乱yin高H肉汁 | 日本妇人成熟A片免费观看 亚洲精品永久在线观看 | 午夜欧美日韩精品久久久久久 | 忍不住亲子性行为中文字幕 | 国产国语高清在线视频二区 | 国产91精品系列在线观看 | 中文字幕一区视频一线 | AV色欲无码人妻中文字幕 | 18禁国产精品久久久久久久久 | 丰满少妇VIDEOSHD | 国产精品毛片久久久久久久 | 久久久这里有精品999 | 人人人人爽人人人人爱 | 国产精品99久久久久久 | 加勒比高清无码二区在线三级免费电影dvd | 三上悠亚激情AV一区二区三区 | 99re热视频在线 | 欧美体内SHE精视频 亚洲国产天堂久久综合网 在线观看亚洲中文字幕 | 国产精品酒店性爱视频 | 久久精品极品盛宴观看 | 又大又爽又硬的曰皮视频 | 内射毛片内射国产夫妻 | 国产超碰人人模人人爽人人添 |