亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国色天香视频免费高清社区,丰满少妇又硬又粗又大视频 ,免费AV岛国大片在线观看
Rabbit Anti-Deltex 1/AP Conjugated antibody (bs-0399R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0399R-AP
英文名稱 Rabbit Anti-Deltex 1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的DTX1抗體
別    名 Deltex protein 1; Deltex; Deltex-1; Deltex1; Dtx1; FXI-T1; Fxit 1; Fxit1; mDTX1; DTX1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Cow, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Deltex-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Deltex is a RING finger ubiquitin ligase which is conserved from Drosophila to Humans and is a regulator of Notch signaling pathway. Deltex regulates both B-cell lineage and splenic marginal-zone B-cell commitment. Deltex is implicated in neurogenesis, lymphogenesis and myogenesis as well as marginal zone B cell differentiation.

Function:
Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

Subunit:
Homodimer. May form a heterodimer with other members of the Deltex family. Interacts with NOTCH1 via its N-terminus region and EIF3F, the interaction is required for NOTCH1 deubiquitination. Interacts with EP300. Forms a heterodimer with BBAP; the heterodimerization leading to an increase of in vitro ubiquitin ligase activity. Interacts with ITCH.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associates with endocytic vesicles. Partially nuclear.

Tissue Specificity:
Widely expressed. Strongly expressed in blood vessel. Also expressed in embryonic nervous system, pancreas, lung, adrenal gland, digestive tube and muscles. Expressed in MZB cells and developing B- and T-cells.

Post-translational modifications:
Ubiquitinated; undergoes 'Lys-29'-linked polyubiquitination catalyzed by ITCH.

Similarity:
Belongs to the Deltex family.
Contains 1 RING-type zinc finger.
Contains 2 WWE domains.

Database links:

Entrez Gene: 1840 Human

Entrez Gene: 14357 Mouse

Omim: 602582 Human

SwissProt: Q86Y01 Human

SwissProt: Q61010 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Deltex1用于老年滯呆、神經(jīng)退行性變的研究。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
性生交片免费无码看人 | 狠狠躁18三区二区一区 | 亚洲AV成人男人的天堂网 | 国产东北三老头伦一肥婆 | 娇喘嗯嗯~轻点啊视频福利 | 永久黄网站色视频免费 | 两口子交换真实刺激高潮 | 综合激情丁香久久狠狠男同 | 涩涩视频在线播放 | 《色诱女教师》在线观看 | 太紧了夹得我的巴好爽欧美 | 无套内谢少妇毛片AAAA片免费 | 久久精品黄AA片一区二区三区 | 亚洲欧洲中文日韩久久AV乱码 | 国产刺激高潮免费不卡 | 国产精品日韩AV无码久久 | 亚洲精品国产SUV | 一本色道久久88综合亚洲精品 | 9191精品国产日本欧美 | 台湾一级毛片永久免费 | 精品无码国产自产野外拍在线 | 奶头好大揉着好爽gif动态 | 国产一级片内射毛片中出91 | 久久天天躁狠狠躁夜夜躁2014 | 免费一级肉体全黄毛片365看片 | 欧美人与性囗牲恔配视频0 国产成人精品久久一区二区三区 | 欧美精品九九99久久在免费线 | 国产精品成人久久久久无码 | 忘忧草日本在线播放WWW | av春色-精品少妇人妻av无码 | 六月婷婷国产精品综合 | 精品一卡2卡三卡4卡乱码毛1 | 真实亲子乱一区二区三区 | 最近中文字幕免费国语 | AV无码播放一级毛片免费野外 | 亚洲AV√最新天堂版资源地址在线官网 | 在线观看欧美亚洲日韩片 | 国产黄A真人一级无码毛片一区二区三区 | 真实国产乱人伦在线视频播放 | 在线观看日韩一区 | 2012中文字幕免费高清 |