亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久久精品久久久久久久久久久 ,A国产一区二区免费入口,91精品国产91
Rabbit Anti-Deltex 1/Cy5 Conjugated antibody (bs-0399R-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0399R-Cy5
英文名稱(chēng) Rabbit Anti-Deltex 1/Cy5 Conjugated antibody
中文名稱(chēng) Cy5標(biāo)記的DTX1抗體
別    名 Deltex protein 1; Deltex; Deltex-1; Deltex1; Dtx1; FXI-T1; Fxit 1; Fxit1; mDTX1; DTX1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,  (predicted: Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Deltex-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Deltex is a RING finger ubiquitin ligase which is conserved from Drosophila to Humans and is a regulator of Notch signaling pathway. Deltex regulates both B-cell lineage and splenic marginal-zone B-cell commitment. Deltex is implicated in neurogenesis, lymphogenesis and myogenesis as well as marginal zone B cell differentiation.

Function:
Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

Subunit:
Homodimer. May form a heterodimer with other members of the Deltex family. Interacts with NOTCH1 via its N-terminus region and EIF3F, the interaction is required for NOTCH1 deubiquitination. Interacts with EP300. Forms a heterodimer with BBAP; the heterodimerization leading to an increase of in vitro ubiquitin ligase activity. Interacts with ITCH.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associates with endocytic vesicles. Partially nuclear.

Tissue Specificity:
Widely expressed. Strongly expressed in blood vessel. Also expressed in embryonic nervous system, pancreas, lung, adrenal gland, digestive tube and muscles. Expressed in MZB cells and developing B- and T-cells.

Post-translational modifications:
Ubiquitinated; undergoes 'Lys-29'-linked polyubiquitination catalyzed by ITCH.

Similarity:
Belongs to the Deltex family.
Contains 1 RING-type zinc finger.
Contains 2 WWE domains.

Database links:

Entrez Gene: 1840 Human

Entrez Gene: 14357 Mouse

Omim: 602582 Human

SwissProt: Q86Y01 Human

SwissProt: Q61010 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Deltex1用于老年滯呆、神經(jīng)退行性變的研究。
版權(quán)所有 2004-2026 www.a6308.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
精品福利一区二区三区免费视频 | 天堂中文在线最新版WWW | 一本到无码高清手机字幕在线播放 | 国产欧美日韩网站 | 奶头好大揉着好爽gif动态 | 波多野结衣AV全免费观 | 青草草在线视频永久免费 | 亚洲欧洲中文日韩久久AV乱码 | 国产亚洲欧美日韩综合综合二区 | 国产乱子经典视频在线观看 | 国产清纯美女爆白浆视频 | 免费一级肉体全黄毛片365看片 | 蜜桃视频一区二区 | 欧美一区二区三区免费播放 | 手机在线精品视频 | 欧美三级片a片在线观看 | 国产成人午夜精品免费视频 | 国产欧美久久久久久精品一区二区 | 久久久久久人妻精品三区 | 在线综合亚洲欧美网站无弹窗 | 国产高清露脸孕妇系列 | 麻婆豆传媒一区二区三 | 久久AV无码专区亚洲桃花岛 | 免费 无码 国产真人视频九色 | 黄色毛片在线观看 | 在线A亚洲老鸭窝天堂AV高清 | 久久久久久久精品一区二区三区 | 黄成人app网站在线看 | 国产精品福利影院 | 亚洲精品国产日韩无码AV永久免费网 | 99精品久久久久久人妻精品 | 美女被C污黄网站免费观看 又粗又硬女人免费视频 | 最近免费中文字幕大全免费版视频 | 国产精品视频第一区二区三区 | 日韩中文字幕免费的视频在线看网站 | 给个网站2021年直接进入的 | 国产一级特黄aaa大片 | 欧美人成在线观看ccc36 | 丰满岳妇乱一区二区三区 | 久久另类精品欧美日韩高清精品不卡 | 亚洲色欲色欲WWW在线丝 |