| 產(chǎn)品編號(hào) | bs-3675R-APC |
| 英文名稱 | Rabbit Anti-R-cadherin/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的R-鈣粘附分子抗體 |
| 別 名 | Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 細(xì)胞粘附分子 糖蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 81kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human R-cadherin(423-475aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues. Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed mainly in brain but also found in other tissues. Similarity: Contains 5 cadherin domains. Database links: Entrez Gene: 1002 Human Entrez Gene: 12561 Mouse Omim: 603006 Human SwissProt: P55283 Human SwissProt: P39038 Mouse SwissProt: Q80ZV4 Mouse Unigene: 473231 Human Unigene: 598638 Human Unigene: 184711 Mouse Unigene: 382094 Mouse Unigene: 392073 Mouse Unigene: 214089 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. R-鈣粘附分子,是依賴鈣離子的細(xì)胞間糖蛋白粘附分子的一種，主要是參與細(xì)胞間同源性粘附、調(diào)控和介導(dǎo)細(xì)胞間相互反應(yīng)，在腫瘤的遷移、分化中起到一定的作用。在腦組織中表達(dá)外，其他組織中已有定位。 |
